Table 4 Predictors of venous thromboembolism in cHP group
Characteristic | Non-VTE | VTE | OR | 95% CI | p-value |
|---|---|---|---|---|---|
No. of patients | 147 (96.7) | 5 (3.3) | |||
Age; median (IQR); years | 52 (43–61) | 53 (52–54) | 1.02 | 0.95–1.10 | 0.653 |
Male gender | 72 (49) | 4 (80) | 4.17 | 0.60–82.6 | 0.128 |
Smoking | |||||
Smokers or ex-smokers | 46 (31) | 3 (60) | 3.29 | 0.53–25.6 | 0.195 |
Comorbidities | |||||
Arterial hypertension Coronary artery disease Diabetes mellitus Congestive heart failure Pulmonary hypertension (by echocardiography) | 86 (59) 14 (9.5) 23 (16) 14 (9.5) 40 (32) | 5 (100) 0 (0) 0 (0) 1 (20) 4 (80) | > 100 0.00 0.00 2.37 8.60 | 0.00–NA – – 0.12–17.5 1.22–171 | 0.022 0.321 0.196 0.489 0.030 |
Treatment | |||||
ASA Systemic steroids Immunosuppressants | 19 (13) 132 (90) 49 (33) | 0 (0) 5 (100) 2 (40) | 0.00 > 100 1.33 | – 0.00–NA 0.17–8.30 | 0.242 0.304 0.759 |
Pulmonary function test | |||||
FVC% predicted FEV1% predicted FEV1%FVC DLco% predicted | 80 (64–98) 77 (61–91) 82 (76–86) 49 (40–62) | 77 (67–90) 66 (50–72) 70 (48–77) 58 (32–67) | 0.99 0.97 0.92 1.00 | 0.95–1.03 0.93–1.02 0.87–0.98 0.95–1.05 | 0.751 0.234 0.008 0.937 |
6-min walking distance (m) | 487 (430–568) | 413 (310–432) | 0.99 | 0.99–1.00 | 0.163 |
D-dimer (µg/ml) | 392 (242–535) | 255 (182–379) | 0.84 | 0.48–1.08 | 0.314 |