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Table 1 Differences between ILD and those without ILD in SRP-IMNM

From: Interstitial lung disease is not rare in immune-mediated necrotizing myopathy with anti-signal recognition particle antibodies

Characteristic

ILD patients (n = 27)

Patients without ILD (n = 33)

p value

Female/male

22/5

23/10

> 0.05

Smoking history

3/27 (11.1%)

2/33 (6.1%)

> 0.05

Age (years)

48.6 ± 14.4

41.2 ± 15.4

< 0.05

Arthritis

1/27 (3.7%)

3/33 (9.1%)

> 0.05

Fever

3/27 (11.1%)

1/33 (3.0%)

> 0.05

Myalgia

11/27 (40.7%)

10/33 (30.3%)

> 0.05

Dysphagia

14/27 (51.9%)

7/33 (21.2%)

< 0.05

AST (U/L)

101.2 ± 89.5

130.8 ± 113.0

> 0.05

ALT (U/L)

126.5 ± 102.9

158.7 ± 105.8

> 0.05

CK (U/L)

2520.4 ± 2409.1

3493.4 ± 3161.7

> 0.05

LDH (U/L)

564.8 ± 316.7

705.1 ± 390.6

> 0.05

Serum ferrtin (ng/L)

162.9 ± 142.5

184.5 ± 178.4

> 0.05

ANA positive

24/27 (88.9%)

27/33 (81.8%)

> 0.05

Ro-52

13/27 (48.1%)

11/33 (33.3%)

> 0.05

SSA

4/27 (14.8%)

4/33 (12.1%)

> 0.05

  1. LDH, lactate dehydrogenase; ALT, alanine transaminase; AST, aspartate transaminase; CK, creatine kinase