Males | Females | p | Never smokers | Ever smokers | p | Age ≤ 50 | Age > 50 | p |
---|---|---|---|---|---|---|---|---|
EGFR (n = 1282) | ||||||||
62/848 (7.3%) | 114/434 (26.3) | < 0.0001 | 62/140 (44.3%) | 114/641 (17.8%) | < 0.0001 | 18/100 (18%) | 158/1182 (13.4%) | 0.2537 |
KRAS (n = 944) | ||||||||
156/619 (25.2%) | 45/325 (13.8%) | 0.0001 | 14/133 (10.5%) | 187/585 (32%) | < 0.0001 | 18/83 (21.7%) | 183/861 (21.2%) | 0.9613 |
BRAF (n = 944) | ||||||||
20/619 (3.2%) | 8/325 (2.5%) | 0.6453 | 2/133 (1.5%) | 26/585 (4.4%) | 0.1825 | 2/83 (2.4%) | 26/861 (3%) | 0.9794 |
ALK (n = 880) | ||||||||
26/592 (4.4%) | 15/288 (5.2%) | 0.7123 | 5/82 (6.1%) | 36/398 (9%) | 0.5140 | 6/57 (10.5%) | 35/823 (4.2%) | 0.0645 |
MET (n = 692) | ||||||||
5/471 (1%) | 9/221 (4.1%) | 0.0247 | 2/75 (2.7%) | 12/345 (3.5%) | 1.000 | 0/46 (0%) | 14/646 (2.1%) | 0.6883 |