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Fig. 4 | BMC Pulmonary Medicine

Fig. 4

From: Simultaneous occurrence of accelerated nodulosis in lungs, liver, and kidneys, and acute exacerbation of interstitial pneumonia in a patient with rheumatoid arthritis: an autopsy case report

Fig. 4

Microscopic findings. Hematoxylin and eosin stained specimen (original magnification; AC × 40; D × 200) were observed under OLYMPUS BX-53 microscope. Photos were captured through a CCD digital camera (Leica DFC295) and recorded by LAS software V4.12. The scale bar is 500 μm (AC) or 100 μm (D). A A rheumatoid nodule of the liver. The nodule consisted of a focus of central necrosis surrounded by palisading granuloma. B The majority of alveolar septa adjacent to the pleura were thickened and densely fibrotic, which caused frequent subpleural honeycombing. C Interstitial changes composed of relatively mature fibrosis and fibroblastic proliferation along with moderate degree of mononuclear cells’ infiltrates. Note detaching alveolar epithelial cells from alveolar septa and focal squamous metaplasia. Those findings were consistent with organizing diffuse alveolar damage. D Cryptococcus pneumonia. The alveolar space was filled with round and pale organisms

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