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Table 1 Demographic and clinical characteristics of patients

From: Risk factor analysis and nomogram for predicting in-hospital mortality in ICU patients with sepsis and lung infection

 

Survived to discharge N = 1191

 

Died in hospital N = 485

P value

Demographics

Age (years)

 

58.84 ± 13.95

62.13 ± 12.60

 < 0.001*

Gender (%)

 Male

 

724 (60.8)

283 (58.4)

0.385

Vital signs

Heart Rate (times/min, %)

0 (60–100)

358 (30.1)

127 (26.2)

 
 

1 (101–120)

418 (35.1)

146 (30.1)

0.003*

 

2 (< 60or 121–140)

276 (23.2)

134 (27.6)

 
 

3 (140–160)

118 ( 9.9)

58 (12.0)

 
 

4 (> 160)

21 (1.8)

20 (4.1)

 

MBP (mmhg, %)

0 (65–110)

226 (19.0)

81 (16.7)

0.191

 

1 (50–64 or 111–130)

618 (51.9)

242 (49.9)

 
 

2 (< 50 or > 160)

347 (29.1)

162 (33.4)

 

Breath rate (times/min, %)

0 (12–24)

254 (21.3)

96 (19.8)

0.525

 

1 (10–11 or 25–34)

641 (53.8)

252 (52.0)

 
 

2 (35–49)

272 (22.8)

127 (26.2)

 
 

3 (< 6 or > 49)

24 (2.0)

10 (2.1)

 

T (℃, %)

0 (36–37.3)

333 (28.0)

184 (37.9)

 < 0.001*

 

1 (37.3–38.2 or 35.001–35.9)

399 (33.5)

177 (36.5)

 
 

2 (38.201–39.1or 34.001–35)

299 (25.1)

81 (16.7)

 
 

3 (39.101–40 or < 34)

135 (11.3)

32 (6.6)

 
 

4(> 40)

25 (2.1)

11 (2.3)

 

SpO2

 

92.00 [89.00, 95.00]

91.00 [88.00, 94.00]

 < 0.001*

Gcs

 

15.00 [14.00, 15.00]

15.00 [12.00, 15.00]

0.002*

Sofa

 

6.00 [4.00, 9.00]

8.00 [5.00, 11.00]

 < 0.001*

SAPSII

 

40.00 [31.00, 49.00]

49.00 [41.00, 59.00]

 < 0.001*

Library tests

Glucose (mmol/L, %)

0 (3.9–7.8)

380 (31.9)

138 (28.5)

0.5

 

1 (7.8–11.1)

390 (32.7)

167 (34.4)

 
 

2 (11.2–16.7 or 1.6–3.8)

276 (23.2)

123 (25.4)

 
 

3 (> 16.7 or < 1.6)

145 (12.2)

57 (11.8)

 

ALBUMIN (g/dl)

 

2.82 ± 0.66

2.66 ± 0.68

 < 0.001*

BILIRUBIN (mg/dl)

 

0.70 [0.40, 1.30]

0.90 [0.50, 2.70]

 < 0.001*

BUN (mg/dl)

 

29.00 [18.00, 47.00]

37.00 [24.00, 58.00]

 < 0.001*

CREATININE (mg/dl)

 

1.40 [0.90, 2.40]

1.60 [1.10, 2.80]

 < 0.001*

WBC (k/ul)

 

13.80 [9.60, 19.90]

14.50 [8.30, 20.90]

0.836

HEMOGLOBIN (g/dl)

 

9.62 ± 1.90

9.32 ± 1.90

0.001*

PLATELET (k/ul)

 

180.00 [112.00, 264.00]

144.00 [60.00, 247.00]

 < 0.001*

APTT(s)

 

34.50 [29.45, 45.70]

37.80 [30.80, 55.00]

 < 0.001*

INR

 

1.40 [1.20, 1.80]

1.60 [1.30, 2.40]

 < 0.001*

PT(s)

 

15.20 [13.70, 18.00]

16.40 [14.20, 21.20]

 < 0.001*

TnT (ug/L)

 

0.08 [0.03, 0.27]

0.10 [0.04, 0.37]

 < 0.001*

NLR

 

8.57 [6.24, 9.94]

9.38 [7.36, 35.52]

 < 0.001*

Blood culture (%)

 

413 (34.7)

193 (39.8)

0.055

Blood gas analysis

PH (%)

0 (7.35–7.45)

426 (35.8)

139 (28.7)

0.011*

 

1 (7.25–7.34 or 7.46–7.55)

434 (36.4)

175 (36.1)

 
 

2 (7.15–7.24 or 7.56–7.65)

220 (18.5)

105 (21.6)

 
 

3 (7.05–7.14)

82 ( 6.9)

47 ( 9.7)

 
 

4 (< 7.05or > 7.66)

29 ( 2.4)

19 ( 3.9)

 

PO2 (mmhg)

 

87.35 ± 45.86

84.21 ± 45.24

0.042

PCO2 (mmhg)

 

48.13 ± 16.00

49.58 ± 17.67

0.243

Oxygenation index

 

160.00 [104.64, 237.00]

147.00 [95.00, 224.00]

0.017*

BICARBONATE (mmol/L)

 

21.00 [18.00, 24.00]

20.00 [17.00, 23.00]

0.002*

LACTATE (mmol/L)

 

2.10 [1.40, 3.65]

2.70 [1.70, 4.80]

 < 0.001*

Complication

CHF (%)

 

427 (35.9)

188 (38.8)

0.287

COPD (%)

 

332 (27.9)

154 (31.8)

0.127

Renal failure (%)

 

240 (20.2)

129 (26.6)

0.005*

Liver disease (%)

 

209 (17.5)

162 (33.4)

 < 0.001*

Neurologic disease (%)

 

184 (15.4)

65 (13.4)

0.321

Cancer (%)

 

112 ( 9.4)

99 (20.4)

 < 0.001*

Diabetes (%)

 

390 (32.7)

143 (29.5)

0.214

Aids (%)

 

14 ( 1.2)

7 ( 1.4)

0.838

Organ transplanted (%)

 

79 ( 6.6)

57 (11.8)

0.001*

Pneumomycosis (%)

 

26 ( 2.2)

21 ( 4.3)

0.024*

Intervention

Vasopressors (%)

 

732 (61.5)

362 (74.6)

 < 0.001*

Vasopressor maximum dose [ug/(dl•min)]

 

1.00 [0.00, 3.00]

2.00 [0.00, 5.00]

 < 0.001*

MV (%)

 

850 (71.4)

406 (83.7)

 < 0.001*

CRRT (%)

 

168 (14.1)

136 (28.0)

 < 0.001*

CVP (%)

 

658 (55.2)

290 (59.8)

0.099

Max CVP value (mmhg)

 

9.00 [9.00, 20.00]

9.00 [9.00, 20.00]

0.509

Fiberscope (%)

 

71 ( 6.0)

37 ( 7.6)

0.25

  1. Heart rate, mean arterial pressure, body temperature, PH value, and Glucose was converted into graded categorical variables
  2. Continuous data are presented as mean ± standard deviation (SD), and median (interquartile ranges),categorical data are presented as frequency (percentage)
  3. CHF congestive heart failure; COPD chronic obstructive pulmonary disease; MBP mean blood pressure; NLR neutrophils to lymphocytes ratio; MV mechanical ventilation; CRRT continuous renal replacement treatment; CVP central vein pressure
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