Table 3 Demographic and clinical data and intubation status
Intubation (−) (n = 50) | Intubation (+) (n = 19) | p value | |
|---|---|---|---|
Characteristics | |||
Male sex (%) | 17 (34%) | 4 (21%) | 0.30 |
Age (years) | 57.4 (35–82) | 58.9 (47–72) | 0.75 |
Hemodynamic parameters | |||
Pulse rate (per min) | 85.8 (79–96) | 90.8 (80–101) | 0.19 |
Systolic BP (mmHg) | 122.42 (112–130) | 124.01 (116–132) | 0.67 |
Diastolic BP (mmHg) | 76.6 (67–86) | 77.1 (68–87) | 0.88 |
Body temperature (°C) | 37.42 (36.9–37.8) | 37.7 (37.3–38) | 0.14 |
Respiratory characteristics | |||
Respiratory rate (breaths per min) | 19.7 (16–20) | 23.5 (18–28) | < 0.01 |
SpO2 (%) | 96.30 (95–98) | 93.74 (93–97) | < 0.01 |
PaO2/FiO2 ratio | 265.8(167.4–334.7) | 199.3(119.7–234.4) | 0.09 |
PaCO2 (mmHg) | 35.5(32.1–38.0) | 35.5(33.7–37.1) | 0.59 |
Biomarkers | |||
WBC (× 1000) (/μL) | 5.6 (4–6.5) | 6.9 (3.6–8.9) | 0.01 |
Lymphocyte count (/μL) | 1174.4 (780–1350) | 683.7 (413–936) | < 0.01 |
Neutrophil count (/μL) | 3375.5 (2029–4526) | 5103.81 (2657–6675) | 0.02 |
CRP (mg/dL) | 5.47 (0.97–9.87) | 13.63 (9.08–10.24) | < 0.01 |
LDH (IU\L) | 272.95 (199–307) | 436.89 (342–510) | < 0.01 |
KL6 (U/mL) | 274.47 (209–289) | 559.93 (221–885) | 0.04 |
Platelet (× 103/μL) | 193.94 (158–238) | 189.26 (146–222) | 0.77 |
D-dimer (μg/mL) | 1.52 (0–1.15) | 10.10 (0.9–6.3) | < 0.01 |
Therapeutic agents | |||
Steroid (%) | 31 (62%) | 17 (89%) | 0.03 |
Heparin (%) | 33 (66%) | 15 (79%) | 0.30 |
Favipiravir (%) | 7 (14%) | 7 (37%) | 0.04 |
Severity scores | |||
APACHE-II score | 16.21 (13–18) | 17.12 (13–22) | 0.73 |
SOFA score | 4.11 (2–5) | 6.29 (4–8) | 0.05 |