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Table 1 Baseline characteristics and blood tests of study patients

From: Association between blood pressure and the risk of biopsy-induced endobronchial hemorrhage during bronchoscopy

Variables

Non-hemorrhaging

Hemorrhaging

P value

n = 400

n = 243

Baseline characteristics

Age, year, median (IQR)

65 (59, 70)

65 (60, 71)

0.146

BMI, kg/m2, median (IQR)

21.8 (19.7, 24.0)

21.5 (19.7, 23.8)

0.308

Gender, n (%)

 

0.133

 Female

96 (24.00)

46 (18.93)

 

 Male

304 (76.00)

197 (81.07)

 

Smoking, n (%)

  

0.020

 Never

163 (40.75)

76 (31.28)

 

 Former

55 (13.75)

49 (20.16)

 

 Current

182 (45.50)

118 (48.56)

 

Location of lesion, n (%)

  

<0.001

 Peripheral bronchi

31 (7.75)

51 (20.99)

 

 Central airway

369 (92.25)

192 (79.01)

 

Stage, n (%)

  

<0.001

 Early

241 (60.25)

108 (44.44)

 

 Advanced

159 (39.75)

135 (55.56)

 

Histological types, n (%)

  

<0.001

 Adenocarcinoma

133 (33.25)

40 (16.46)

 

 Squamous cell carcinoma

177 (44.25)

145 (59.67)

 

 SCLC

69 (17.25)

45 (18.52)

 

 Others

21 (5.25)

13 (5.35)

 

Hypertension, n (%)

  

0.719

 No

303 (75.75)

181 (74.49)

 

 Yes

97 (24.25)

62 (25.51)

 

Diabetes, n (%)

  

0.683

 No

379 (94.75)

232 (95.47)

 

 Yes

21 (5.25)

11 (4.53)

 

CHD, n (%)

  

0.626

 No

388 (97.00)

234 (96.30)

 

 Yes

12 (3.00)

9 (3.70)

 

COPD, n (%)

  

0.967

 No

374 (93.50)

227 (93.42)

 

 Yes

26 (6.50)

16 (6.58)

 

Different components of blood pressure, mmHg, median (IQR)

   

 SP

131 (119, 144)

130 (116, 145)

0.173

 DP

77 (70, 85)

78 (70, 88)

0.331

 MAP

96 (88, 104)

95 (86, 106)

0.920

 PP

53 (43, 64)

52 (40, 61)

0.015

 PP/DP, median (IQR)

0.68 (0.54, 0.84)

0.65 (0.50, 0.79)

0.012

Laboratory values, median (IQR)

   

 WBC (×109/L)

6.7 (5.4, 8.4)

6.9 (5.7, 8.8)

0.155

 Hemoglobin (g/dL)

12.8 (11.6, 13.9)

12.8 (11.4, 14.0)

0.403

 Platelets (×109/L)

220 (171, 278)

231 (173, 287)

0.256

 CRP (mg/L)

6.7 (1.1, 24.7)

10.7 (2.4, 40.2)

0.011

 PT (S)

13.1 (12.5, 13.7)

12.7 (11.6, 13.4)

0.063

 APTT (S)

35.4 (32.5, 38.8)

33.9 (30.7, 37.6)

0.006

 Triglycerides (mmol/L)

1.1 (0.8, 1.5)

1.0 (0.8, 1.3)

0.079

 TC (mmol/L)

4.1 (3.5, 4.8)

4.1 (3.5, 4.7)

0.375

 HDL-C (mmol/L)

1.2 (1.0, 1.4)

1.1 (0.9, 1.3)

0.026

 LDL-C (mmol/L)

2.8 (2.3, 3.3)

2.8 (2.3, 3.2)

0.290

  1. BMI, body mass index; SP, systolic pressure; DP, diastolic pressure; MAP, mean arterial pressure; PP, pulse pressure; PP/DP, pulse pressure to diastolic pressure ratio; SCLC, small-cell lung carcinoma; CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; WBC, white blood cell; CRP, C-reactive protein; PT, prothrombin time; APTT, activated partial thromboplastin time; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol
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