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Table 1 Baseline characteristics of the patients in different clusters

From: Identification of the molecular subgroups in asthma by gene expression profiles: airway inflammation implications

Variables Total Cluster I Cluster II χ2/z/t P valuea
Number 47 17 30   
Age, year, median (Q1, Q3) 60 (49, 68) 68 (63, 77) 56 (43, 63) − 3.369 0.001
Gender, n (%) 0.021 0.886
 Female 27 10 (58.8) 17 (56.7)   
 Male 20 7 (41.2) 13 (43.3)   
Smoking status, n (%) 0.221 0.638
 Never 27 9 (52.9) 18 (60)   
 Former/current 20 8 (47.1) 12 (40)   
Airway inflammation, n (%)b
 Eosinophilic 17 10 (58.8) 7 (23.3) 5.794 0.015
 Neutrophilic 12 7 (41.2) 5 (16.7) 3.365 0.067
 Paucigranulocytic 18 0 (0) 18 (60.0) 16.179 < 0.001
 Mixed Granulocytic 0 0 (0) 0 (0) 3.596 0.0579
  1. aCompared between Cluster I and Cluster II
  2. bAsthma inflammatory phenotype was assigned based on a sputum eosinophil cutoff of greater than 2% and a sputum neutrophil cutoff of greater than 61%