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Table 1 Patients’ characteristics

From: A comparative study of the sarcopenia screening in older patients with interstitial lung disease

 

Overall

(n = 78)

AWGS 2019 criteria classification

Sarcopenia

(n = 25)

Non-sarcopenia

(n = 53)

P value

Age, years

71 (67–77)

72 (68–77)

71 (67–82)

0.499

Sex male, %

51 (65)

16 (64)

35 (66)

1.00

BMI, kg/m2

24 (20–26)

23 (20–28)

24 (22–26)

0.855

Diagnosis, IIPs/other ILDs

49/29

15/10

34/19

0.804

Duration from diagnosis, months

3 (1–16)

2 (1–12)

6 (1–23)

0.227

Corticosteroid, %

12 (15)

6 (24)

6 (11)

0.184

Antifibrotic drugs, %

16 (21)

4 (16)

12 (23)

0.564

Long-term oxygen therapy, %

11 (14)

5 (20)

6 (11)

0.316

ILD-GAP score, point

3 (2–4)

3 (2–4)

3 (2–4)

0.551

mMRC dyspnea scale, grade

2 (1–2)

2 (1–2)

1 (1–2)

0.754

PaCO2 at rest, mmHg

41 (38–46)

40 (38–44)

42 (38–51)

0.417

PaO2 at rest, mmHg

80 (63–91)

86 (73–94)

75 (61–91)

0.219

FVC, %

85 (68–97)

85 (63–93)

85 (72–98)

0.316

FEV1, %pred

90 (75–101)

90 (69–103)

90 (77–101)

0.863

FEV1/FVC, %

78 (72–86)

80 (72–87)

78 (72–85)

0.514

DLCO, %

64 (45–80)

70 (45–83)

60 (45–80)

0.271

KL-6, U/ml

715 (451–1165)

662 (474–1168)

740 (407–1155)

0.768

HF, kgf

26 (20–33)

23 (19–33)

27 (22–34)

0.167

QF, kgf

28 (19–35)

23 (16–33)

29 (20–36)

0.169

Calf circumference, cm

33 (30–35)

33 (30–37)

34 (30–35)

0.996

SMI, kg/m2

7 (6–7)

7 (5–7)

7 (6–8)

0.201

SPPB, point

11 (11–12)

12 (11–12)

12 (11–12)

0.912

SARC-F, point

1 (0–2)

1 (0–4)

1 (0–2)

0.486

SARC-CalF, point

2 (0–11)

11 (0–12)

1 (0–11)

0.171

6MWD, m

424 (355–500)

392 (308–509)

442 (371–500)

0.317

ADL score

6 (6–6)

6 (6–6)

6 (6–6)

0.204

K-BILD, point

54 (47–64)

53 (44–68)

54 (48–62)

0.684

Psychological symptoms

51 (43–63)

49 (43–67)

52 (42–60)

0.720

Breathlessness and activities

44 (34–53)

40 (31–55)

46 (37–53)

0.232

Chest symptoms

73 (64–85)

73 (47–85)

73 (64–85)

0.779

  1. Categorical variables were analyzed using Fisher's exact test, while continuous variables with unpaired t-tests and Mann–Whitney U test. Values are median (interquartile range) or numbers (percentage) of subjects
  2. ADL score, activities of daily living score; BMI, Body Mass Index; CalF, calf circumference; DLCO, diffusion capacity for carbon monoxide; %FEV1, percentage of forced expiratory volume in one second; FVC, forced vital capacity; HF, handgrip force; IIPs, idiopathic interstitial pneumonias; ILD-GAP, interstitial lung disease-gender, age, lung physiology score; K-BILD, King’s Brief Interstitial Lung Disease, KL-6, Krebs von den Lungen-6; mMRC, Modified Medical Research Council; 6MWD, six-minute walking distance; PaCO2, partial pressure of carbon dioxide; PaO2, partial pressure of oxygen; %pred, percent predicted; QF, quadriceps force; the SARC-F, the strength, assistance in walking, rising from a chair, climbing stairs, and falls; SARC-CalF, SARC-F combined with calf circumference; SMI, skeletal muscle index; SPPB, short physical performance battery; %VC, percentage of volume capacity
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BMC Pulmonary Medicine

ISSN: 1471-2466

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