STOP: an open label crossover trial to study ICS withdrawal in patients with a combination of obesity and low-inflammatory asthma and evaluate its effect on asthma control and quality of life

Table 1 Overview of procedures during STOP trial. These procedures will be used in both crossover period 1 and crossover period 2

	Time (weeks)	− 2	0 and 18	4 and 22	6,8,13 and 24,26,31	18 and 36
	Period (1 or 2)	1	1 and 2	1 and 2	1 and 2	1 and 2
	Visit type	Inclusion	Run-in	Baseline	Follow up	Follow up
Activity/Assesment
Live		x	x	x		x
Telephone					x
Check inclusion criteria		x
Informed consent		x
Medication check		x
Prior medical history		x
Comorbidities		x
Anthropometrics		x		x		x
Exacerbation frequency		x	x	x	x	x
Questionnaires		x	x	x	x	x
Blood samples				x		x
Scalp Hair				x		x
Lung function test*			x	x		x
eNose				x		x
Study information		x	x	x	x	x
Prescriptions			x	x	x	x
SAE form		Thoughout study

ISSN: 1471-2466