Table 2 Characteristics of ILD in 66 patients with pSS
From: Interstitial lung disease in Primary Sjögren's syndrome
ILD-onset | |
|---|---|
Time of ILD onset (n, %) | |
Before pSS onset | 14, 21.21% |
Concomitant with pSS | 13, 19.70% |
After pSS onset | 39, 59.09% |
Pulmonary symptoms (n, %) | |
Dry cough | 32, 48.48% |
Sputum production | 23, 34.85% |
Chest tightness | 14, 21.21% |
Dyspnea | 19, 28.79% |
Fever | 19, 28.79% |
Recurrent pulmonary infections | 16, 24.24% |
Baseline pulmonary function | |
TLC, % predicted | 74.32 ± 17.27 |
FVC, % predicted | 82.50 (71.25–97) |
FEV1, % predicted | 84 (71–96.75) |
DLCO, % predicted | 58.82 ± 21.04 |
FEV1/FVC | 100 (95.25–103) |
RV, % predicted | 72.24 ± 24.09 |
RV/TLC | 94.87 ± 17.56 |
FEF25, % predicted | 74.4 ± 28.59 |
FEF50, % predicted | 64.30 ± 24.20 |
FEF75, % predicted | 61.07 ± 27.76 |
HRCT findings (n, %) | |
Ground glass opacities | 58, 87.88% |
Irregularities in pleural margins | 47, 71.21% |
Septal/sub pleural lines | 54, 81.82% |
Honeycombing appearance | 19, 28.79% |
Sub pleural cysts | 27, 40.90% |
parenchymal micronodules/nodules | 61, 92.42% |
HRCT scan pattern (n, %) | |
NSIP | 42, 63.64% |
UIP | 20, 30.30% |
LIP | 3, 4.55% |
COP | 1, 1.52% |
HRCT CoVR quantification | |
HRCT extent | 6 (4–9) |
HRCT severity | 6 (5–15) |
HRCT total score | 12 (9–24) |