Skip to main content

Table 1 Patient characteristics

From: The new useful high-resolution computed tomography finding for diagnosing fibrotic hypersensitivity pneumonitis: “hexagonal pattern”: a single-center retrospective study

 

Fibrotic HP n = 23

IPF n = 48

P-value

Age, years

68 (56–76)

67 (49–77)

0.362

Gender (male/female), n

15/8

35/13

0.506

Smoking status (ex/never)

12/11

32/16

0.239

WBC, μL

6250 (2530–10,300)

6365 (3400–13,500)

0.531

LDH, IU/L

232 (149–305)

211 (139–360)

0.428

CRP, mg/dL

0.11 (0.01–1.50)

0.14 (0.01–1.79)

0.526

KL-6, U/mL

1772 (578–8437)

834 (286–4666)

< 0.001

SP-D, pg/mL

393 (84–1111)

222 (45–897)

0.049

Pulmonary function

   

 FVC % pred

87.1 (63.8–125.5)

85.8 (44.9–137.1)

0.461

 FEV1/FVC ratio

78.0 (65.4–96.6)

78.3 (59.5–100.0)

0.606

 FEV1% pred

87.9 (67.0–115.4)

83.5 (52.1–129.9)

0.363

 DLCO % pred

78.5 (49.9–125.1)

76.5 (29.1–123.5)

0.588

BAL fluida

   

 Total cell count, × 104/μL

26.9 (2.6–69.1)

24.3 (0.2–62.1)

0.750

 Macrophages, %

40.5 (4.0–91.0)

83.0 (17.0–96.0)

< 0.001

 Lymphocytes, %

55.2 (7.5–95.0)

11.3 (1.6–70.0)

< 0.001

 Neutrophils, %

1.4 (0–10.0)

2.0 (0–39.0)

0.425

 Eosinophils, %

0.8 (0–6.0)

2.0 (0–18.0)

0.060

 CD4/8 ratio

3.9 (0.2–9.8)

1.7 (0–8.4)

0.005

  1. Data are expressed as median (range) or numbers of patients
  2. HP, hypersensitivity pneumonitis; IPF, idiopathic pulmonary fibrosis; WBC, white blood cell; LDH, lactate dehydrogenase; CRP, C-reactive protein; KL-6, Krebs von den Lungen-6; SP-D, surfactant protein-D; FVC, forced vital capacity; FEV1, forced expiratory volume in one second; DLCO, diffusion lung capacity for carbon monoxide; BAL, bronchoalveolar lavage
  3. afor BALF, n = 20 (fibrotic HP), n = 39 (IPF)