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Table 2 MUC5B concentration and inflammatory biomarkers in BALF of NSCAP patients and SCAP patients

From: Respiratory MUC5B disproportion is involved in severe community-acquired pneumonia

 

NSCAP

SCAP

p value

Muncins in BALF

MUC5B concentration (µg/ml)

13.56 (5.92–25.79)

8.20 (4.97–14.03)

0.011

Total protein contentration (mg/ml)

0.38 (0.15–1.10)

0.68 (0.46–1.69)

0.002

MUC5B/Total protein percent (%)

3.66 (1.50–5.56)

1.38 (0.73–1.76)

< 0.001

Inflammatory biomarkers in BALF

IL6 (pg/ml)

1.81 (1.22–3.08)

5.83 (2.50–15.73)

< 0.001

IL10 (pg/ml)

0.18 (0.11–0.32)

0.15 (0.12–0.27)

0.632

IFNγ (pg/ml)

2.98 (1.90–4.04)

3.27 (2.11–4.69)

0.195

IL13 (pg/ml)

30.00 (28.78–31.66)

31.08 (30.20–33.35)

0.004

IL17 (pg/ml)

9.53 (6.52–11.23)

12.04 (9.47–17.54)

< 0.001

  1. Data presented as median (interquartile range)
  2. CAP, community-acquired pneumonia; NSCAP, non-severe CAP; SCAP, severe CAP; BALF, bronchoalveolar lavage fluid