Table 1 Demographic and clinical characteristics of different groups of enrolled patients
Non-COPD | GOLD I | GOLD II | GOLD III | GOLD IV | p value | |
|---|---|---|---|---|---|---|
Number, N (%) | 83 (29.26%) | 18 (6.33%) | 82 (28.87%) | 80 (28.17%) | 21 (7.39%) | – |
Age, year | 67 (59,68) | 59.50 (55.75,65) | 67.50 (60,76.25) | 66.50 (62.25,71) | 69 (67,69) | < 0.01 |
Sex, man, N (%) | 43 (51.81%) | 14 (77.78%) | 68 (82.93%) | 71 (88.75%) | 19 (90.47%) | < 0.01 |
BMI, kg/m2 | 28.65 (25.80,29.75) | 23.72 (23.29,24.52) | 24.04 (21.60,25.68) | 23.17 (21.03,26.01) | 18.69 (17.98,19.60) | < 0.01 |
Current smoker, N (%) | 49 (59.04%) | 10 (55.56%) | 67 (81.71%) | 59 (73.75%) | 18 (85.71%) | – |
Acute exacerbations (frequency/year) | 0 (0,1) | 0 (0,1.5) | 1 (1,3) | 3 (1,4) | 3.5 (2.75,4) | < 0.01 |
FEV1 | 1.56 (1.21,1.68) | 2.54 (2.50,2.54) | 1.62 (1.39,1.91) | 1.11 (0.96,1.28) | 0.78 (0.66,0.92) | < 0.01 |
FVC | 2.45 (2.06,2.85) | 3.70 (3.70,3.75) | 2.58 (2.30,3.08) | 2.09 (1.88,2.37) | 1.57 (1.35,1.93) | < 0.01 |
FEV1% | 53.20 (41.20,58.30) | 81.00 (81.00,83.00) | 57.10 (52.90,66.40) | 39.80 (35.93,44.18) | 26.70 (22.80,28.65) | < 0.01 |
FEV1/FVC% | 61.11 (57.35,71.36) | 67.79 (66.11,68.65) | 62.92 (58.44,67.22) | 51.65 (48.01,58.34) | 50.00 (45.16,56.99) | < 0.01 |
RV/TLC% | 52.79 (49.81,63.84) | 39.81 (38.47,56.70) | 55.85 (46.97,61.99) | 60.90 (54.11,65.34) | 66.41 (62.27,71.26) | < 0.01 |
LAA-950 | 4.90 (4.50,27.50) | 6.25 (4.80,7.58) | 20.60 (13.38,27.43) | 25.30 (15.53,32.58) | 27.50 (24.90,31.50) | < 0.01 |
Visual subtypes | 3 (2,5) | 2 (1.75,4) | 4 (4,5) | 5 (5,6) | 6 (6,6) | < 0.01 |