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Table 1 Clinical record of the patient during treatment

From: Diagnosis of lung squamous cell carcinoma based on metagenomic Next-Generation Sequencing

Date

Infectious indicators

Treatment

Body temperature (highest)

7.10

WBC: 19.83 * 10^9/L ↑ GR: 85% ↑ CRP: 108.3 mg/L ↑ PCT: 0.056 ng/mL

Before hospitalization

40.0 °C

7.20

WBC: 30.13 * 10^9/L ↑ GR: 86.1% ↑ CRP: 72.67 mg/L ↑ PCT: 2.25ug/L ↑

Vancomycin

40.3 °C

7.21

CEA: 8.68 ng/mL ↑ SCC: 3.10 ng/mL ↑ CYFRA21_1: 6.37 ng/mL ↑

7.23

WBC: 30.64 * 10^9/L ↑ GR: 90.3% ↑ CRP: 149.24 mg/L ↑

+ Voricanozole

7.24

Metagenomic Next-Generation Sequencing result indicated tumour, clinicians performed lung puncture

Meropenem

40.0 °C

7.28

WBC: 19.37 * 10^9/L ↑ GR: 85.9% ↑ CRP: 153.02 mg/L ↑

+ Voriconazole

 

Report of lung puncture showed tumor, SLC was considered

7.29

CEA: 9.59 ng/mL ↑ SCC: 4.3 ng/mL ↑

 

37.5 °C

7.30

Operation (radical resection of lung cancer)

 

7.31

WBC: 9.62 * 10^9/L ↑ GR: 76.9% ↑

CRP: 124.36 mg/L ↑ PCT: 0.35%↑

Cefoperazone sodium sulbactam

 

8.13

Discharged from hospital

  

9.8

WBC: 7.19 * 10^9/L GR: 57.3% CRP: 20.1 mg/L ↑ PCT: 0.22%

CEA: 1.84 ng/mL SCC: 0.4 ng/mL CYFRA21_1: 1.9 ng/mL

 

Normal (< 37 °C)

  1. WBC white blood cell, GR granulocytes, CRP C-reactive protein, PCT plateletcrit, CEA carcinoembryonic antigen, SCC squamous cell carcinoma, CYFRA21_1 cytokeratin-19 fragment
  2. “↑” indicates higher than normal range