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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: The zinc transporter ZIP12 regulates monocrotaline-induced proliferation and migration of pulmonary arterial smooth muscle cells via the AKT/ERK signaling pathways

Fig. 1

The expression of ZIP12 and MCT-induced proliferation in vivo. Immunofluorescence analysis were performed. A Representative images of double immunofluorescence staining for ZIP12 (green) and α-SMA (red) in lung tissues (magnification, ×200) and quantification of ZIP12 immunofluorescence intensity (n = 8 rats per group). B ZIP12 mRNA expression in lung tissues (n = 8 rats per group). Representative Western blot and summarized data showing the protein expression of C ZIP12, D phosphorylated and total AKT, E phosphorylated and total ERK1/2, F PCNA and G cyclin D1 in rat lung tissues (n = 8 rats per group). Ctrl control, PAH pulmonary arterial hypertension, MCT monocrotaline. The data are expressed as the mean ± standard deviation. Error bars represented standard deviation. **P < 0.01

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BMC Pulmonary Medicine

ISSN: 1471-2466

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