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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: The zinc transporter ZIP12 regulates monocrotaline-induced proliferation and migration of pulmonary arterial smooth muscle cells via the AKT/ERK signaling pathways

Fig. 2

MCT treatment enhanced the expression of ZIP12 in PASMCs. A Rat PASMCs exhibited long spindle-shape (magnification, ×100) and were identified by immunofluorescence staining for α-SMA (magnification, ×400). B ZIP12 (red) colocalized with the cell membrane dye DiO (green) in PASMCs (magnification, ×200). C Representative Western blot and summarized data showing the protein expression of ZIP12 in Ctrl-PASMCs and MCT-PAH-PASMCs (n = 8 rats per group). Ctrl control, PAH pulmonary arterial hypertension, PASMCs pulmonary arterial smooth muscle cells, MCT monocrotaline. The data are expressed as the mean ± standard deviation. Error bars represented standard deviation. **P < 0.01

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