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Table 1 Non-pharmaceutical DHC resource consumption per patient (diagnosis and follow-up by FC) and unit costs

From: The economic burden of pulmonary arterial hypertension in Spain

 

Resource consumption (n)

Unit cost (€)

Diagnosis

Ref

1 year follow-up

Ref

EUR

Ref

FC I-II

FC III

FC IV

Medical visits

        

 General practitioner

5.0

Experts

2.6

3.8

5.9

[66]

€51.88–€69.24

[40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55]

 Nurse

–

2.8

5.5

8.8

[66]

€25.89–€27.70

[40,41,42,43,44,45, 47,48,49,50, 52,53,54, 57, 58, 60, 64, 65]

 Specialised care

4.0

2.8

4.2

7.1

[66]

€89.15–€158.80

[40,41,42,43, 45, 47, 49,50,51,52,53, 55,56,57,58,59,60]

 Emergency care visits

–

3.5

3.6

7.2

[67]

€153.07

[40,41,42,43, 45, 47,48,49,50,51, 51,52,53,54,55,56, 60, 63,64,65, 102, 103]

Tests

        

 Electrocardiogram

2.5

[10] and experts

2.5

3.5

4.0

[10]

€20.90

[42, 43, 46, 47, 49, 51, 53, 55, 57, 60,61,62]

 Cardiopulmonary exercise test

1.0

1.0

1.0

1.0

[10]

€311.00

[42,43,44,45,46, 49,50,51,52,53,54,55, 57, 63]

 Six-Minute Walk Test

1.0

2.5

3.5

4.0

[10]

€106.53

[46, 49, 51,52,53,54, 57, 64]

 Echocardiogram

1.0

1.0

1.0

2.0

[10]

€103.87

[41,42,43, 45,46,47, 50, 52,53,54,55,56,57, 60, 61]

 Biochemistry

2.5

2.5

3.5

4.0

[10]

€83.55

[43, 52, 53, 55, 58, 61]

 Extended biochemistry

–

1.0

1.0

1.0

[10]

€188.17

[43, 46, 52,53,54,55, 57, 58, 61, 64]

 Blood gas analysis/(V/Q Scan)

1.0/(1.0)

1.0

1.0

2.0

[10]

€44.50 (€331.04)

[42, 43, 45, 46, 54, 56, 57, 61]

 Right heart catheterisation

1.0

1.0

1.0

1.0

[10]

€1,055.38

[41, 43, 46, 47, 51, 54, 60]

 CT angiogram

1.0

1.0

1.0

1.0

Experts

€217.53

[42, 49, 52,53,54,55,56,57, 60, 104]

 Oxygen saturation

–

2.5

3.5

6.0

[68]

€24.75

[46]

 Chest X-ray

2.5

1.0

1.0

2.0

[68]

€20.00

[42, 43, 45,46,47,48,49,50, 52,53,54,55,56,57]

Hospitalisations

–

 

9.4

10.8

22.8

[67]

€601.22

[42, 43, 46, 47, 49,50,51,52,53,54,55,56,57, 60, 63]

Transplants

–

 

–

7.5

8.5

[69, 70]

€85,629.57

[79]

  1. (1) The time for which the resources are estimated is annual. (2) Unit costs refer to the median costs of the first and follow-up visits at the different Spanish AACC. (3) The visit to the emergency department/unscheduled urgent visit to the referral centre is a weighting (40% and 60%, respectively). (4) The cost of lung scan is an average of the median unit costs of perfusion and ventilation lung scan. (5) For days of hospitalisation in FC I and II, a weighting of 10% and 90%, respectively, was assumed. (6) We assumed that a total of 16 PAH-lung transplants were performed during 2020 in Spain
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