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Table 2 Histopathological results of patients with pulmonary infectious disease with suspicion of infection with no identified pathogen

From: Diagnostic performance of the metagenomic next-generation sequencing in lung biopsy tissues in patients suspected of having a local pulmonary infection

Patient ID

Symptom duration before admission (days)

Age (years)

Histopathology results

Clinical diagnosis

P8

60

50

Inflammatory cells

Lung abscess

P9

90

66

Inflammatory cells with few fibrosis

Lung abscess

P12

10

48

Inflammatory cells with few fibrosis

Pulmonary infection

P13

10

23

Inflammatory lesion

Pulmonary infection

P15

30

71

Organizing pneumonia

Pulmonary infection

P27

700

71

Inflammatory cells with necrosis

Lung abscess

P32

10

67

Inflammatory lesion with necrosis

Pulmonary infection

P33

30

83

Organizing pneumonia

Pulmonary infection

P34

10

63

Fibrous connective tissue; chronic inflammatory cell infiltration in lung tissue

Pulmonary infection

P35

7

49

Blood clots; infiltration of inflammatory cells in lung tissue

Pulmonary infection

P36

2

56

Inflammatory cells with necrosis

Lung abscess

P37

60

63

Lung tissue; partial alveolar wall dust deposition

Pulmonary infection

P48

90

54

Pneumonic lesions with fibrosis and carbon deposition

Lung abscess

P49

30

66

Inflammatory cells infiltration in a few broken fibrous tissue

Pulmonary infection

P51

30

61

Mild hyperplasia of alveolar epithelium; histiocyte proliferation in alveolar cavity and alveolar septum

Pulmonary infection

P58

3650

71

Fibrotic interstitium with edema, hyperemia; no alveolar tissue

Pulmonary infection

P61

7

75

Hyperplastic fibrous tissue with chronic inflammatory cell infiltration; a small amount of bleeding and necrosis

Spherical pneumonia

P70

1000

61

Microstructural hyperplasia in the alveolar cavity and pulmonary interstitium; focal hyaline degeneration and a little chronic inflammatory cell infiltration

Pulmonary infection

P72

365

60

Fibrin-like exudates in the alveolar cavity; alveolar septum thickening with fibrosis and chronic inflammatory cell infiltration

Pulmonary infection

P76

30

55

Fibrous tissue hyperplasia

Pulmonary infection

P84

10

61

Fibrous tissue hyperplasia with chronic inflammatory cell infiltration; organic pneumonia

Lung abscess

P91

150

42

Interstitial fibrosis, histiocyte and lymphocyte infiltration

Lung abscess

P92

1

45

Fibrous tissue with lymphocyte and plasma cell infiltration

Pulmonary infection

P93

270

67

Two small pieces of coagulative necrosis; Pulmonary interstitial fibrous tissue hyperplasia with alveolar epithelial hyperplasia; PAS (-); Acid-fast staining (-); Silver staining (-)

Pulmonary infection

P99

20

73

Fibrous tissue cells, scattered and small clusters of glandular epithelial cells

Lung abscess

P100

1

25

Interstitial fibrous tissue hyperplasia with scattered lymphoid hyperplasia

Lung abscess

P106

365

78

Mild hyperplasia of well-differentiated alveolar epithelium with fibrous tissue hyperplasia; vitreous degeneration and chronic inflammatory cell infiltration; a small amount of fibrous exudation

Pulmonary infection