From: The significance of serum S100 calcium-binding protein A4 in silicosis
 | CG (n = 12) | Silicosis (n = 42) | p-value |
---|---|---|---|
Male/female | 10/2 | 41/1 | 0.234 |
Age (yrs) | 40.92 ± 11.49 | 46.60 ± 5.95 | 0.063 |
Smoking pack-years (yrs) | 15.00 (2.50, 20.00) | 13.50 (4.25, 23.75) | 0.742 |
Years of occupational exposure to silica dust (yrs) | 9.56 ± 10.07 | 15.26 ± 7.75 | 0.114 |
BMI | 24.19 (20.18, 26.64) | 21.76 (20.05, 23.84) | 0.213 |
FVC (l) | 3.38 ± 0.52 | 3.24 ± 0.74 | 0.725 |
FVC% pre | 87.30 ± 8.16 | 71.51 ± 14.27 | 0.037 |
FEV1 (l) | 2.73 ± 0.45 | 2.33 ± 0.79 | 0.333 |
FEV1% pre | 85.45 (72.98, 87.20) | 60.30 (48.55, 72.98) | 0.021 |
FEV1/FVC (%) | 80.22 ± 1.10 | 69.96 ± 14.21 |  < 0.01 |
Vcmax (l) | 3.42 ± 0.54 | 3.26 ± 0.68 | 0.642 |
IC (l) | 2.01 ± 0.05 | 2.09 ± 0.69 | 0.485 |
PEF (l/s) | 3.88 (2.91, 3.90) | 2.95 (2.35, 4.29) | 0.416 |
PEF25 (l/s) | 3.88 (2.82, 3.90) | 2.81 (2.04, 3.69) | 0.214 |
PEF50 (l/s) | 3.48 (2.49, 3.61) | 1.98 (1.29, 3.18) | 0.123 |
PEF75 (l/s) | 1.42 (1.23, 1.70) | 0.97 (0.52, 1.44) | 0.072 |
Stage of silicosis (n, %) |  |  | – |
Stage I | – | 9 (21.43%) |  |
Stage II | – | 13 (30.95%) |  |
Stage III | – | 20 (47.62%) |  |