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Table 1 Clinical characteristics of study subjects

From: The significance of serum S100 calcium-binding protein A4 in silicosis

  CG
(n = 12)
Silicosis
(n = 42)
p-value
Male/female 10/2 41/1 0.234
Age (yrs) 40.92 ± 11.49 46.60 ± 5.95 0.063
Smoking pack-years (yrs) 15.00 (2.50, 20.00) 13.50 (4.25, 23.75) 0.742
Years of occupational exposure to silica dust (yrs) 9.56 ± 10.07 15.26 ± 7.75 0.114
BMI 24.19 (20.18, 26.64) 21.76 (20.05, 23.84) 0.213
FVC (l) 3.38 ± 0.52 3.24 ± 0.74 0.725
FVC% pre 87.30 ± 8.16 71.51 ± 14.27 0.037
FEV1 (l) 2.73 ± 0.45 2.33 ± 0.79 0.333
FEV1% pre 85.45 (72.98, 87.20) 60.30 (48.55, 72.98) 0.021
FEV1/FVC (%) 80.22 ± 1.10 69.96 ± 14.21  < 0.01
Vcmax (l) 3.42 ± 0.54 3.26 ± 0.68 0.642
IC (l) 2.01 ± 0.05 2.09 ± 0.69 0.485
PEF (l/s) 3.88 (2.91, 3.90) 2.95 (2.35, 4.29) 0.416
PEF25 (l/s) 3.88 (2.82, 3.90) 2.81 (2.04, 3.69) 0.214
PEF50 (l/s) 3.48 (2.49, 3.61) 1.98 (1.29, 3.18) 0.123
PEF75 (l/s) 1.42 (1.23, 1.70) 0.97 (0.52, 1.44) 0.072
Stage of silicosis (n, %)   
Stage I 9 (21.43%)  
Stage II 13 (30.95%)  
Stage III 20 (47.62%)  
  1. The value of P was in bold indicating P < 0.05
  2. BMI, body mass index; FVC, forced volume capacity; FEV1, forced expiratory volume in 1 s; FVC% pre, percentage of predicted forced vital capacity; FEV1/FVC, ratio of forced expiratory volume in one second to forced vital capacity; FEV1% pre, percentage of predicted forced expiratory volume in 1 s; Vcmax, maximum vital capacity; IC, deep inspiratory capacity; PEF, peak expiratory flow; PEF25, peak expiratory flow at 25% of vital capacity; PEF50, peak expiratory flow at 50% of vital capacity; PEF75, peak expiratory flow at 75% of vital capacity