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Table 2 Number of ILD patients who reported ILD and non-ILD lung disease in their family (1 or more relatives)

From: Clustering of lung diseases in the family of interstitial lung disease patients

Reported disease in family All Sarc HP IPF uPF Non-IPF IIP aidILD oILD
N (%) 1164 644 87 109 103 54 93 74
Any ILD or non-ILD lung disease 801 (69) 430 (67) 61 (70) 79 (73) 78 (76) 35 (65) 66 (71) 52 (70)
Any ILD 174 (15) 103 (16) 10 (12) 26 (24) 20 (19) 1 (2) 7 (8) 7 (10)
Sarcoidosis 109 (9) 90 (14) 4 (5) 3 (3) 5 (5) 0 3 (3) 4 (5)
Pulmonary fibrosis 54 (5) 7 (1) 5 (6) 22 (20) 15 (15) 0 4 (4) 1 (1)
Remaining ILD 20 (2) 11 (2) 1 (1) 2 (2) 3 (3) 1 (2) 0 2 (3)
Any non-ILD lung disease 750 (64) 395 (61) 59 (68) 72 (66) 72 (70) 35 (65) 65 (70) 52 (70)
Asthma 253 (22) 160 (25) 21 (24) 17 (16) 9 (9) 7 (13) 18 (19) 21 (28)
Bronchitis 177 (15) 101 (16) 19 (22) 8 (7) 8 (8) 9 (17) 16 (17) 16 (22)
COPD 120 (10) 65 (10) 16 (18) 8 (7) 12 (12) 5 (9) 10 (11) 4 (5)
Emphysema 94 (8) 45 (7) 8 (9) 11 (10) 12 (12) 6 (11) 6 (7) 6 (8)
Pneumonia 82 (7) 35 (5) 9 (10) 11 (10) 10 (10) 3 (6) 7 (8) 7 (10)
Tuberculosis 114 (10) 56 (9) 8 (9) 10 (9) 16 (16) 7 (13) 9 (10) 8 (11)
Lung cancer 286 (25) 153 (24) 15 (17) 39 (36) 24 (23) 12 (22) 25 (27) 18 (24)
Lung disease n.s 186 (16) 85 (13) 15 (17) 20 (18) 25 (24) 12 (22) 14 (15) 15 (20)
  1. Sarc = sarcoidosis; HP = hypersensitivity pneumonitis; IPF = idiopathic pulmonary fibrosis; uPF = unclassifiable pulmonary fibrosis; non-IPF IIP = an idiopathic interstitial pneumonia, other than IPF; aidILD = autoimmune disease interstitial lung disease; oILD = other interstitial lung disease; n.s. = not specified