From: Clustering of lung diseases in the family of interstitial lung disease patients
Patient diagnosis group | Self-reported disease in family | Unadjusted | Adjusted for age | Adjusted for sex and age | |||
---|---|---|---|---|---|---|---|
 | Significantly higher frequency of disease in the family | ||||||
IPF | any ILD | 1.9 (1.2–3.1) | 2.6 (1.5–4.3) | 2.6 (1.6–4.4) | |||
Sarcoidosis | sarcoidosis | 4.3 (2.6–7.1) | 3.3 (1.9–5.8) | 3.3 (1.9–5.8) | |||
IPF | pulmonary fibrosis | 8.1 (4.5–14.5) | 7.9 (4.1–15.1) | 9.2 (4.7–17.9) | |||
uPF | pulmonary fibrosis | 4.5 (2.4–8.4) | 3.9 (1.9–7.9) | 4.1 (2.0–8.2) | |||
HP | COPD | 2.1 (1.2–3.8) | 2.4 (1.3–4.2) | 2.3 (1.3–4.2) | |||
IPF | lung cancer | 1.8 (1.2–2.8) | 2.2 (1.4–3.4) | 2.3 (1.4–3.5) | |||
 | Significantly lower frequency of disease in the family | ||||||
Non-IPF IIP | any ILD | 0.1 (0.0–0.7) | 0.1 (0.0–0.8) | 0.1 (0.0–0.8) | |||
Sarcoidosis | pulmonary fibrosis | 0.1 (0.1–0.2) | 0.1 (0.0–0.2) | 0.1 (0.0–0.2) | |||
Sarcoidosis | non-ILD lung disease | 0.7 (0.6–0.9) | 0.6 (0.5–0.8) | 0.6 (0.5–0.8) | |||
Sarcoidosis | lung disease, n.s | 0.6 (0.5–0.9) | 0.6 (0.4–0.9) | 0.6 (0.4–0.9) |