Table 5 Comparison of reported lung disease in the family between patients with sporadic and familial sarcoidosis or pulmonary fibrosis
From: Clustering of lung diseases in the family of interstitial lung disease patients
| Â | Sarcoidosis | pulmonary fibrosis | ||
|---|---|---|---|---|
Sporadic | Familial | Sporadic | Familial | |
n = 554 | n = 90 | n = 175 | n = 37 | |
Disease in relatives, n (%): | Â | Â | Â | Â |
Sarcoidosis | 0 (0) | 90 (100) | 7 (4) | 1 (3) |
Pulmonary fibrosis | 6 (1) | 1 (1) | 0 (0) | 37 (100) |
Remaining ILD | 8 (1) | 3 (3) | 3 (2) | 2 (5) |
Non-ILD lung disease | 337 (61) | 58 (64) | 118 (67) | 26 (70) |
Asthma | 136 (25) | 24 (27) | 21 (12) | 5 (14) |
Bronchitis | 84 (15) | 17 (19) | 15 (9) | 1 (3) |
COPD | 55 (10) | 10 (11) | 16 (9) | 4 (11) |
Emphysema | 38 (7) | 7 (8) | 13 (7) | 10 (27)* P 0.002 OR 4.6 (1.8–11.6) |
Pneumonia | 33 (6) | 2 (2) | 19 (11) | 2 (5) |
Tuberculosis | 49 (9) | 7 (8) | 21 (12) | 5 (14) |
Lung cancer | 127 (23) | 26 (29) | 46 (26) | 17 (46)* P 0.017 OR 2.4 (1.2–4.9) |
Lung disease n.s | 70 (13) | 15 (17) | 37 (21) | 8 (22) |