Factor | Group | Control | CTEPH | P-value |
---|---|---|---|---|
 |  | (n = 22) | (n = 11) |  |
Age | Years | 65.5 ± 11.6 | 65.5 ± 12.2 | 0.94 |
Sex | Female/male | 14-Aug | 07-Apr | 1 |
BMI |  | 23.0 ± 4.3 | 23.7 ± 6.1 | 0.89 |
History of acute PE | Â | No data | 9 | Â |
History of DVT | Â | No data | 5 | Â |
Disease duration from onset to diagnosis | (months) | No data | 52.5 ± 56.9 |  |
NYHA classification | 1/2/3/4 | No data | 0/7/4/0 | Â |
Location of thrombus* | Â | No data | Main PA: 6 | Â |
 |  |  | Lobar PA: 4 |  |
 |  |  | Segmental PA: 1 |  |
Hemodynamics | Â | Â | Â | Â |
Mean PAP | (mmHg) | No data | 44.1 ± 9.1 |  |
PAR | (dyne sec cm−5) | No data | 748 ± 254 |  |
CI | (L/min/m2) | No data | 2.43 ± 0.51 |  |
Medication | Â | Â | Â | Â |
Proton pump inhibitors |  | 2 | 6 |  < 0.01 |
Antibiotics | Â | 0 | 0 | 1 |
Laxatives | Â | 0 | 0 | 1 |
Antiflatulents | Â | 0 | 1 | 0.3 |
sGC stimulators |  | 0 | 8 |  < 0.01 |