Variables in WLL fluid | Group H (n = 13) | Group L (n = 11) | P |
---|
TNF-α (pg·ml−1) | 10.96 ± 3.04 | 10.76 ± 2.44 | 0.36 |
IL-1β (pg·ml−1) | 14.09 ± 9.16 | 11.08 ± 5.91 | 0.87 |
IL-10 (pg·ml−1) | 0.72 ± 0.42 | 1.58 ± 1.03* | 0.01 |
ROS (U·ml−1) | 561.16 ± 76.33 | 517.92 ± 122.40 | 0.30 |
MDA (nmol·ml−1) | 3.64 ± 0.97 | 3.40 ± 0.33 | 0.50 |
SOD (U·ml−1) | 56.64 ± 23.65 | 82.04 ± 7.14* | < 0.01 |
- Measurement data are expressed as means ± SD. *Was statistically significant compared with Group H, P < 0.05
- Group H, high negative suction pressure group; Group L, low negative suction pressure group
- The levels of TNF-α, IL-1β and IL-10 in WLL fluid were detected by using rat-specific enzyme-linked immunosorbent assay (ELISA) kits. Levels of ROS, MDA, and SOD in WLL fluid were measured by using commercial kits
- WLL whole lung lavage; TNF-α tumor necrosis factor-α; IL-1β interleukin-1β; IL-10 interleukin-10; ROS reactive oxygen species; MDA malondialdehyde; SOD superoxide dismutase