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Table 3 Variables in WLL fluid on inflammation and the oxidation system

From: Lung injury induced by different negative suction pressure in patients with pneumoconiosis undergoing whole lung lavage

Variables in WLL fluid Group H (n = 13) Group L (n = 11) P
TNF-α (pg·ml−1) 10.96 ± 3.04 10.76 ± 2.44 0.36
IL-1β (pg·ml−1) 14.09 ± 9.16 11.08 ± 5.91 0.87
IL-10 (pg·ml−1) 0.72 ± 0.42 1.58 ± 1.03* 0.01
ROS (U·ml−1) 561.16 ± 76.33 517.92 ± 122.40 0.30
MDA (nmol·ml−1) 3.64 ± 0.97 3.40 ± 0.33 0.50
SOD (U·ml−1) 56.64 ± 23.65 82.04 ± 7.14*  < 0.01
  1. Measurement data are expressed as means ± SD. *Was statistically significant compared with Group H, P < 0.05
  2. Group H, high negative suction pressure group; Group L, low negative suction pressure group
  3. The levels of TNF-α, IL-1β and IL-10 in WLL fluid were detected by using rat-specific enzyme-linked immunosorbent assay (ELISA) kits. Levels of ROS, MDA, and SOD in WLL fluid were measured by using commercial kits
  4. WLL whole lung lavage; TNF-α tumor necrosis factor-α; IL-1β interleukin-1β; IL-10 interleukin-10; ROS reactive oxygen species; MDA malondialdehyde; SOD superoxide dismutase