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Table 3 Variables in WLL fluid on inflammation and the oxidation system

From: Lung injury induced by different negative suction pressure in patients with pneumoconiosis undergoing whole lung lavage

Variables in WLL fluid

Group H (n = 13)

Group L (n = 11)

P

TNF-α (pg·ml−1)

10.96 ± 3.04

10.76 ± 2.44

0.36

IL-1β (pg·ml−1)

14.09 ± 9.16

11.08 ± 5.91

0.87

IL-10 (pg·ml−1)

0.72 ± 0.42

1.58 ± 1.03*

0.01

ROS (U·ml−1)

561.16 ± 76.33

517.92 ± 122.40

0.30

MDA (nmol·ml−1)

3.64 ± 0.97

3.40 ± 0.33

0.50

SOD (U·ml−1)

56.64 ± 23.65

82.04 ± 7.14*

 < 0.01

  1. Measurement data are expressed as means ± SD. *Was statistically significant compared with Group H, P < 0.05
  2. Group H, high negative suction pressure group; Group L, low negative suction pressure group
  3. The levels of TNF-α, IL-1β and IL-10 in WLL fluid were detected by using rat-specific enzyme-linked immunosorbent assay (ELISA) kits. Levels of ROS, MDA, and SOD in WLL fluid were measured by using commercial kits
  4. WLL whole lung lavage; TNF-α tumor necrosis factor-α; IL-1β interleukin-1β; IL-10 interleukin-10; ROS reactive oxygen species; MDA malondialdehyde; SOD superoxide dismutase