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Table 4 Prognostic factors of 28-day mortality in patients who underwent TBLB or TBLC

From: Transbronchial lung biopsy versus transbronchial lung cryobiopsy in critically ill patients with undiagnosed acute hypoxemic respiratory failure: a comparative study

 

Univariate analysis

Multivariate analysis

HR

95% CI

p value

HR

95% CI

p value

Male

0.741

0.350–1.568

0.433

0.844

0.304–2.344

0.745

Age

1.014

0.986–1.043

0.319

0.995

0.961–1.031

0.797

CCI

1.004

0.840–1.199

0.968

0.929

0.709–1.216

0.591

Immunocompromised host

0.939

0.388–2.128

0.825

1.213

0.396–3.712

0.735

IPPV or ECMO support

1.554

0.747–3.233

0.238

0.700

0.197–2.482

0.581

APACHE II score

1.066

1.013–1.122

0.014

0.932

0.845–1.027

0.153

SOFA score

1.225

1.094–1.372

 < 0.001

1.673

1.319–2.122

 < 0.001

PT, s

1.125

0.961–1.316

0.161

   

APTT, s

1.021

0.981–1.064

0.310

   

Platelet, *109/L

0.997

0.994–1.001

0.132

   

Procedure

0.749

0.341–1.646

0.472

0.637

0.189–2.151

0.468

Number of biopsy

1.067

0.832–1.369

0.610

   

Moderate bleeding

0.545

0.139–2.294

0.408

0.279

0.035–2.226

0.229

Pneumothorax

2.374

0.824–6.841

0.109

7.448

1.649–33.647

0.009

ΔAPACHE II ≥ 5

0.594

0.081–4.366

0.608

0.812

0.083–7.935

0.858

ΔSOFA ≥ 3

2.115

0.639–7.006

0.220

5.034

0.992–25.536

0.051

Pathological diagnosis

0.727

0.349–1.511

0.393

0.620

0.195–1.967

0.417

MDD diagnosis

0.648

0.309–1.357

0.250

0.193

0.047–0.792

0.022

Treatment modifications

0.300

0.144–0.626

0.001

0.204

0.065–0.638

0.006

  1. CCI, Charlson Comorbidity Index; IPPV, invasive positive pressure ventilation; ECMO, Extracorporeal membrane oxygenation; PFR, PaO2/FiO2 ratio; APACHE II score, acute physiology and chronic health evaluation II score; SOFA score, sequential organ failure assessment score; PT, prothrombin time; APTT, partial thromboplastin time; MDD, Multidisciplinary discussion
  2. Bold for statistically significant (p value < 0.05)
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BMC Pulmonary Medicine

ISSN: 1471-2466

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