Fig. 3

Pathway analysis of differential metabolites in the serum of mice with pulmonary fibrosis. A KEGG substance pathway analysis, the color of the dot represents p-value, and the redder the dot, the more significant the enrichment. The size of the point represents the pathway impact. The pathway impact is a weight calculation based on topology analysis, the larger the pathway impact is, the more plausible the corresponding pathway is. B Simplified scheme of Glycerolipid pathway and Glycerophospholipid pathway and the connection with them. Red, indicating upregulation of metabolites; blue, indicating downregulation of metabolites