Table 1 Baseline characteristics and comparison of respiratory function between baseline and 5 years after observation in patients with COPD
Baseline | 5 years after | |
|---|---|---|
Number of participants | 65 | 65 |
Age | 69.7 (1.0) | |
Sex; male: female | 53:12 | |
Body mass index | 22.5 (0.4) | 21.8 (0.4) |
Smoking history (pack-years) | 51.7 (1.9) | |
Current: former | 13: 52 | 8: 57 |
mMRC | 1.3 (0.1) | 1.6 (0.1)** |
CAT | 6.0 (0.6) | 6.9 (0.6)* |
GOLD stage | ||
I, n (%) | 11 (16.9) | 13 (20.0) |
II, n (%) | 39 (60.0) | 35 (53.8) |
III, n (%) | 14 (21.5) | 15 (23.1) |
IV, n (%) | 1 (1.5) | 2 (3.1) |
Spirometry | ||
FEV1 (L) | 1.66 (0.07) | 1.57 (0.08)** |
FEV1 (% predicted) | 62.8 (2.0) | 63.1 (2.2) |
FVC (% predicted) | 88.7 (1.7) | 90.3 (2.0) |
FEV1/FVC (%) | 56.4 (1.1) | 54.8 (1.2)* |
MMEF (% predicted) | 19.9 (1.2) | 19.3 (12) |
PEF (% predicted) | 68.7 (2.5) | 68.1 (3.3) |
IOS | ||
R5 (kPa/L/s) | 0.29 (0.01) | 0.33 (0.02)** |
R20 (kPa/L/s) | 0.21 (0.01) | 0.21 (0.01) |
R5-R20 (kPa/L/s) | 0.08 (0.01) | 0.11 (0.01)** |
X5 (kPa/L/s) | − 0.13 (0.01) | − 0.17 (0.02)* |
Fres (Hz) | 18.7 (0.7) | 20.4 (0.8)** |
AX (kPa/L) | 0.92 (0.11) | 1.42 (0.17)** |