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Table 4 Statistics by diagnosis compared to other diagnoses

From: Validation of nasal tracheal aspiration in children with lung disease

 

Similarity

Sensitivity

Specificity

PPV

NPV

CF >< Rare lung disease

Coherence growtha

0.099

0.011

0.504

0.060

0.928

Concordance bacteriab

0.678

0.015

 

0.032

 

CF >< Airway malformation

Coherence growth

0.009

0.006

0.141

0.006

0.142

Concordance bacteria

0.123

0.015

 

0.015

 

CF >< other lung-related disease

Coherence growth

0.066

0.014

1

0.004

0.724

Concordance bacteria

0.377

0.528

 

0.753

 

Rare lung disease >< Airway malformation

Coherence growth

0.349

1

0.025

0.391

0.158

Concordance bacteria

0.273

0.647

 

0.910

 

Rare lung disease >< other lung-related disease

Coherence growth

0.792

1

0.518

0.260

0.655

Concordance bacteria

0.195

0.003

 

0.017

 

Airway malformation >< other lung-related disease

Coherence growth

0.57

1

0.161

0.630

0.074

Concordance bacteria

0.01

0.002

 

0.007

 
  1. Bold: p-values ≤ 0.05 are statistically significant
  2. PPV positive predictive value, NPV negative predictive value
  3. aCoherence growth: Agreement is only based on positive growth or not in NTA and BAL
  4. bConcordance bacteria: Complete concordance concerning pathogen bacteria between NTA and BAL