Table 4 Median (interquartile range) changes in QTc in the stroke and control population
From: QTc prolongation is associated with severe desaturations in stroke patients with sleep apnea
Pre-desaturation QTc (ms) | ΔQTc within-desaturation (ms) | ΔQTc post-desaturation (ms) | |
|---|---|---|---|
Desaturation duration | Stroke population | ||
10 ≤ s < 20 | 418.9 (405.4–439.4) | 0.8 (− 8.9–9.7) | 2.3 (− 7.4–11.0) |
20 ≤ s < 30 | 422.3 (409.5–453.5) | − 1.1 (− 8.0–8.7) | − 1.0 (− 11.3–7.8) |
30 ≤ s < 45 | 427.4 (412.7–457.2)* | 3.4 (− 6.9–12.3) | 2.4 (− 6.3–10.5) |
≥ 45 s | 430.6 (412.6–460.9)* | 7.5 (− 3.0–14.8) * | 0.5 (− 10.3–10.8) |
Desaturation depth | |||
3% ≤ ΔSpO2 < 5% | 424.8 (409.1–454.9) | 0.6 (− 8.9–11.1) | 0.8 (− 11.5–9.5) |
5% ≤ ΔSpO2 < 7% | 424.8 (414.1–458.3) | − 1.4 (− 9.7–10.5) | − 1.4 (− 9.8–9.4) |
7% ≤ ΔSpO2 < 9% | 424.5 (408.9–444.1) | 4.6 (− 3.2–12.3)* | 2.0 (− 4.8–7.8)* |
ΔSpO2 ≥ 9% | 424.3 (413.7–437.4) | 7.4 (− 1.1–14.9)* | 3.7 (− 5.6–10.0)† |
Desaturation duration | Control population | ||
10 ≤ s < 20 | 416.2 (390.9–436.7) | 1.4 (− 5.2–8.1) | − 1.7 (− 7.9–5.9) |
20 ≤ s < 30 | 405.8 (392.1–424.9) | 0.8 (− 5.1–6.4) | 0.6 (− 6.2–7.6) |
30 ≤ s < 45 | 401.5 (391.2–413.4)* | 0.3 (− 4.5–5.6) | 2.2 (− 3.6–10.1)* |
≥ 45 s | 403.2 (391.3–414.5)* | 3.7 (− 2.6–8.9)† | − 0.4 (− 4.9–6.2) |
Desaturation depth | |||
3% ≤ DSpO2 < 5% | 402.6 (387.0–423.1) | 1.8 (− 3.7–6.8) | 0.9 (− 4.7–7.9) |
5% ≤ SpO2 < 7% | 405.0 (390.8–422.0) | 1.8 (− 3.5–8.2) | 0.8 (− 5.8–9.5) |
7% ≤ SpO2 < 9% | 405.5 (397.3–421.4) | 1.3 (− 6.5–6.1) | 1.2 (− 7.8–6.7) |
SpO2 ≥ 9% | 404.2 (396.3–414.9) | − 0.7 (− 7.3–5.1)* | 2.6 (− 4.9–9.6) |