Table 4 Sensitivity, specificity, accuracy, AUC, marginal AUC, marginal AUC p-value, diagnostic odds ratio, and p-value for each cut-point of TB-SS screening test estimated from an elderly population as compared with the results of the GeneXpert MTB/RIF (n = 302)
Cut-point | Sensitivity (%) | Specificity (%) | Accuracy (%) | AUC | Marginal AUC | Marginal AUC p-value | Dx OR | p |
|---|---|---|---|---|---|---|---|---|
≥ 2 | 98.72 | 3.13 | 27.81 | 0.51 | – | – | 2.48 | 0.398 |
≥ 3 | 94.87 | 8.48 | 30.79 | 0.52 | 0.01 | 0.570 | 1.71 | 0.341 |
≥ 4 | 83.33 | 22.77 | 38.41 | 0.53 | 0.01 | 0.526 | 1.47 | 0.258 |
≥ 5 | 73.08 | 36.61 | 46.03 | 0.55 | 0.02 | 0.389 | 1.57 | 0.122 |
≥ 6 | 61.54 | 54.02 | 55.96 | 0.58 | 0.03 | 0.186 | 1.88 | 0.019 |
≥ 7 | 60.26 | 64.29 | 63.25 | 0.62 | 0.04 | < 0.001 | 2.73 | < 0.001 |
≥ 8 | 52.56 | 73.21 | 67.88 | 0.63 | 0.01 | 0.730 | 3.03 | < 0.001 |
≥ 9 | 48.72 | 80.80 | 72.52 | 0.65 | 0.02 | 0.184 | 4 | < 0.001 |
≥ 10 | 41.03 | 88.39 | 76.16 | 0.65 | 0 | 0.977 | 5.3 | < 0.001 |
≥ 11 | 29.49 | 93.30 | 76.82 | 0.61 | − 0.04 | 0.091 | 5.83 | < 0.001 |
≥ 12 | 14.10 | 97.77 | 76.16 | 0.56 | − 0.05 | 0.012 | 7.19 | < 0.001 |
≥ 13 | 7.69 | 99.55 | 75.83 | 0.54 | − 0.02 | 0.114 | 18.58 | 0.007 |
≥ 14 | 3.85 | 100.00 | 75.17 | 0.52 | − 0.02 | 0.129 | 1 | – |
≥ 15 | 1.28 | 100.00 | 74.50 | 0.51 | − 0.01 | 0.155 | 1 | – |