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Table 2 Association of STAS with PD-1/PD-L1 expression

From: An individual nomogram can reliably predict tumor spread through air spaces in non-small-cell lung cancer

Data

 

All patients (n = 3075)

n (%)

STAS

p

Present (n = 617)

Absent (n = 2458)

n (%)

n (%)

PD1 tumor cell

 < 1%

2868 (98.86)

573 (19.98)

2295 (80.02)

0.661

 ≥ 1%

33 (1.14)

5 (15.15)

28 (84.85)

PD1 stromal cell

 < 1%

510 (17.61)

54 (10.59)

456 (89.41)

 < 0.001

1–5%

1206 (41.64)

218 (18.08)

988 (81.92)

5–10%

697 (24.07)

166 (23.82)

531 (76.18)

 ≥ 10%

483 (16.68)

140 (28.99)

343 (71.01)

PD-L1(SP28-8) tumor cell

 < 1%

1879 (85.76)

311 (16.55)

1568 (83.45)

 < 0.001

1–5%

86 (3.93)

31 (36.05)

55 (63.95)

5–10%

48 (2.19)

18 (37.50)

30 (62.50)

 ≥ 10%

178 (8.12)

65 (36.52)

113 (63.48)

PD-L1(SP28-8) stromal cell

 < 1%

718 (33.04)

108 (15.04)

610 (84.96)

 < 0.001

1–5%

353 (16.24)

94 (26.63)

259 (73.37)

5–10%

139 (6.40)

53 (38.13)

86 (61.87)

 ≥ 10%

963 (44.32)

164 (17.03)

799 (82.97)

PD-L1(SP142) tumor cell

 < 1%

1588 (78.34)

255 (16.06)

1333 (83.94)

 < 0.001

1–5%

102 (5.03)

32 (31.37)

70 (68.63)

5–10%

67 (3.31)

28 (41.79)

39 (58.21)

 ≥ 10%

270 (13.32)

106 (39.26)

164 (60.74)

PD-L1(SP142) stromal cell

 < 1%

423 (20.91)

49 (11.58)

374 (88.42)

 < 0.001

1–5%

365 (18.04)

88 (24.11)

277 (75.89)

5–0%

245 (12.11)

85 (34.69)

160 (65.31)

 ≥ 10%

990 (48.94)

196 (19.80)

794 (80.20)

  1. PD-1, Programmed death-1; PD-L1, programmed death-ligand 1