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Table 1 Comparison of baseline characteristics between survivors and non-survivors

From: Prognostic implication of bronchoalveolar lavage fluid analysis in patients with Pneumocystis jirovecii pneumonia without human immunodeficiency virus infection

 

Total (n = 178)

Survivors (n = 158)

Non-survivors (n = 20)

P value

Age, years

60.0 ± 11.8

59.6 ± 11.1

62.9 ± 16.6

0.407

Male sex

96 (53.9)

89 (56.3)

7 (35.0)

0.095

Ever smoker

66 (37.1)

60 (38.0)

6 (30.0)

0.625

Underlying disease

    

 Hematological malignancy

58 (32.6)

53 (33.5)

5 (25.0)

0.467

 Solid cancer

70 (39.3)

59 (37.3)

11 (55.0)

0.149

 Organ transplantation*

42 (23.6)

41 (25.9)

1 (5.0)

0.048

 Autoimmune disease

31 (17.4)

27 (17.1)

4 (20.0)

0.756

Diabetes mellitus

45 (25.3)

40 (25.3)

5 (25.0)

 > 0.999

Chronic kidney disease

30 (16.9)

27 (17.1)

3 (15.0)

 > 0.999

Previous steroid use**

27 (15.2)

20 (12.7)

7 (35.0)

0.016

Prophylaxis with TMP/SMX

9 (5.1)

6 (3.8)

3 (15.0)

0.066

Initial laboratory tests

    

 Albumin, g/dL (n = 177)

2.4 ± 0.5

2.4 ± 0.5

2.2 ± 0.4

0.079

 C-reactive protein, mg/dL (n = 177)

12.3 ± 8.9

11.4 ± 8.6

19.4 ± 8.6

 < 0.001

 Lactate dehydrogenase, IU/L (n = 153), median [IQR]

375.0 [271.0–474.5]

364.0 [268.8–470.5]

427.0 [346.0–584.0]

0.069

 Procalcitonin, ng/mL (n = 126), median [IQR]

0.13 [0.06–0.41]

0.13 [0.05–0.41]

0.16 [0.06–1.04]

0.593

 β-D-glucan, pg/mL (n = 132), median [IQR]

72.8 [0.0–301.6]

55.4 [0.0–314.9]

98.5 [0.0–262.4]

0.801

 Absolute neutrophil count, cells/μL, median [IQR]

2775.0 [1547.5–5172.5]

2775.0 [1605.0–4947.5]

2960.0 [822.5–6767.5]

0.924

Neutropenia within 6 months before admission

81 (45.5)

74 (46.8)

7 (35.0)

0.350

  1. Data are expressed as mean ± standard deviation or number (%) unless otherwise indicated
  2. The Fisher’s exact test was performed to analyze the variable with a value of less than 5
  3. TMP/SMX, trimethoprim/sulfamethoxazole; IQR, interquartile range
  4. *Organ transplantation includes 25 solid organ transplantations and 17 hematopoietic stem cell transplantations
  5. ** ≥ 20 mg/day prednisolone and ≥ 4 weeks