Table 1 ICU basic characteristics (n = 140)
All patients (n = 140) | 28 days Survivors (n = 44) | 28 days Non-survivors (n = 96) | p Value | |
|---|---|---|---|---|
Age (Median, range) | 73 (44–99) | 74 (47–99) | 72 (44–93) | 0.054 |
BMI (Median, range) | 21 (13–33) | 21 (13–32) | 21 (15–33) | 0.971 |
Sex | ||||
Male | 87 (62.1) | 29 (65.9) | 58 (60.4) | 0.578 |
Female | 53 (37.9) | 15 (34.1) | 38 (39.6) | |
Smoking history | ||||
Ever smoker | 76 (54.3) | 24 (54.5) | 52 (54.2) | 1.00 |
Never smoker | 64 (45.7) | 20 (45.5) | 44 (45.8) | |
ECOG | ||||
0–1 | 62 (44.3) | 15 (34.1) | 47 (49.0) | 0.142 |
> = 2 | 78 (55.7) | 29 (65.9) | 49 (51.0) | |
Driver mutation | 60 (42.9) | 20 (45.5) | 40 (41.7) | 0.715 |
Treatment lines | 2 (0–10) | 1 (0–8) | 2 (0–10) | 0.142 |
APACHEII (Median, SE) | 14 (± 0.66) | 12 (± 0.98) | 15 (± 0.83) | 0.019 |
NIPPVa | 137 (97.9) | 43 (97.7) | 94 (97.9) | 1.000 |
Recent anticancer treatment | ||||
Nilb | 52 (37.1) | 18 (40.9) | 34 (35.4) | 0.110 |
Chemotherapy | 38 (27.1) | 8 (18.2) | 30 (31.3) | |
Target therapy | 37 (26.4) | 16 (36.4) | 21 (21.9) | |
Radiotherapy | 13 (9.3) | 2 (4.5) | 11 (11.5) | |
GCS | 14 (3–15) | 15 (3–15) | 14 (3–15) | 0.172 |
PaO2/FiO2 (Mean, SD) | 174.2 ± 104 | 209.6 ± 111.4 | 157.9 ± 96.7 | 0.006 |
PaCO2 | 42.5 ± 16.4 | 41.3 ± 13.8 | 43.1 ± 17.5 | 0.542 |
pH | 7.40 ± 0.11 | 7.41 ± 0.11 | 7.40 ± 0.01 | 0.430 |
Lactate | 28.8 ± 24.5 | 26.2 ± 29 | 30 ± 22.5 | 0.499 |
Neutropenia | 7 (5) | 1 (2.3) | 6 (6.3) | 0.433 |
Reasons of ICU admission | ||||
Sepsis/infection | 73 (52.1) | 21 (47.7) | 52 (54.2) | 0.553 |
Cancer related | 40 (28.6) | 13 (29.5) | 27 (28.1) | |
Treatment related | 15 (10.7) | 7 (15.9) | 8 (8.3) | |
Underlying disease | 12 (8.6) | 3 (6.8) | 9 (9.4) | |