Table 2 Observed deaths and SMRs for causes of death after diagnosis of SCLC
From: Causes of death following small cell lung cancer diagnosis: a population-based analysis
Deaths by time after diagnosis | ||||||||
|---|---|---|---|---|---|---|---|---|
< 1 y | 1–3 y | > 3 y | Total deaths | |||||
Observed, no. (%) | SMR (95% CI) | Observed, no. (%) | SMR (95% CI) | Observed, no. (%) | SMR (95% CI) | Observed, no. (%) | SMR (95% CI) | |
Cause of death | ||||||||
All | 29,536 (100) | 54.96 (54.33–55.59)* | 11,040 (100) | 43.00 (42.20–43.81)* | 1 900 (100) | 8.19 (7.83–8.57)* | 42,476 (100) | 41.39 (41.00–41.79)* |
SCLC | 26,306 (89.1) | 583.5 (576.5–590.6)* | 10,115 (91.6) | 475.8 (466.6–485.2)* | 1258 (66.2) | 73.55 (69.55–77.7)* | 37,679 (88.7) | 451.5 (447.0–456.1)* |
Other cancers | 1355 (4.6) | 12.56 (11.90–13.25)* | 358 (3.2) | 6.86 (6.17–7.61)* | 67 (3.5) | 1.49 (1.16–1.90)* | 1780 (4.2) | 8.68 (8.29–9.10)* |
Noncancer causes | 1875 (6.3) | 4.88 (4.66–5.10)* | 567 (5.1) | 3.09 (2.84–3.36)* | 575 (30.3) | 3.38 (3.11–3.67)* | 3017 (7.1) | 4.09 (3.94–4.24)* |
Septicemia | 106 (5.7) | 12.76 (10.45–15.44)* | 29 (5.1) | 7.15 (4.79–10.26)* | 17 (3.0) | 4.60 (2.68–7.37)* | 152 (5.0) | 9.47 (8.0211.10)* |
Infectious/parasitic diseases including HIV infection | 56 (3.0) | 10.52 (7.94–13.66)* | 4 (0.7) | 1.55 (0.42–3.97) | 9 (1.6) | 4.29 (1.96–8.13)* | 69 (2.3) | 6.90 (5.37–8.73)* |
Diabetes mellitus | 34 (1.8) | 1.89 (1.31–2.64)* | 6 (1.1) | 0.69 (0.25–1.51) | 9 (1.6) | 1.2 (0.55–2.27) | 49 (1.6) | 1.43 (1.06–1.89)* |
Alzheimer’s disease | 7 (0.4) | 0.5 (0.20–1.03) | 4 (0.7) | 0.57 (0.16–1.46) | 26 (4.5) | 3.17 (2.07–4.65)* | 37 (1.2) | 1.27 (0.89–1.75) |
Cardiovascular diseases | 593 (31.6) | 4.09 (3.77–4.44)* | 200 (35.3) | 3.0 (2.59–3.44)* | 128 (22.3) | 2.14 (1.79–2.55)* | 921 (30.5) | 3.40 (3.18–3.62)* |
Cerebrovascular diseases | 75 (4.0) | 2.65 (2.09–3.32)* | 29 (5.1) | 2.18 (1.46–3.14)* | 45 (7.8) | 3.63 (2.65–4.86)* | 149 (4.9) | 2.76 (2.34–3.24)* |
Pneumonia and influenza | 76 (4.1) | 6.89 (5.43–8.62)* | 15 (2.6) | 2.94 (1.65–4.85)* | 22 (3.8) | 4.65 (2.92–7.05)* | 113 (3.7) | 5.42 (4.47–6.51)* |
COPD/ associated conditions | 292 (15.6) | 8.09 (7.19–9.07)* | 86 (15.2) | 4.91 (3.93–6.06)* | 151 (26.3) | 9.38 (7.94–11.00)* | 529 (17.5) | 7.59 (6.96–8.26)* |
Chronic liver disease/cirrhosis | 15 (0.8) | 2.19 (1.22–3.61)* | 4 (0.7) | 1.17(0.32–2.99) | 6 (1.0) | 2.11 (0.77–4.59) | 25 (0.8) | 1.90 (1.23–2.81)* |
Nephritis, nephrotic syndrome, and nephrosis | 31 (1.7) | 2.89 (1.97–4.11)* | 12 (2.1) | 2.35 (1.21–4.10)* | 11 (1.9) | 2.37 (1.18–4.23)* | 54 (1.8) | 2.64 (1.98–3.44)* |
Accidents and adverse effects of medications | 70 (3.7) | 4.57 (3.56–5.77)* | 29 (5.1) | 3.85 (2.58–5.53)* | 34 (5.9) | 5.07 (3.51–7.08)* | 133 (4.4) | 4.50 (3.77–5.33)* |
Suicide and self-inflicted injury | 23 (1.2) | 5.45 (3.45–8.17)* | 8 (1.4) | 3.98 (1.72–7.85)* | 2 (0.3) | 1.27 (0.15–4.57) | 33 (1.1) | 4.23 (2.91–5.93)* |
Other | 497 (26.5) | 6.10 (5.57–6.66)* | 141 (24.9) | 3.50 (2.95–4.13)* | 115 (20.0) | 2.89 (2.39–3.47)* | 753 (25.0) | 4.66 (4.33–6.01)* |