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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: LncRNA LINC00511 promotes COL1A1-mediated proliferation and metastasis by sponging miR-126-5p/miR-218-5p in lung adenocarcinoma

Fig. 2

Linc00511 downregulation inhibits LUAD cell proliferation, migration, and invasion and promotes LUAD cell apoptosis. A The Linc00511 knockdown efficiency in A549 and PC9 cells was determined by RT–qPCR. The proliferation and viability of A549 and PC9 cells after silencing Linc00511 was evaluated by CCK-8 (B) and colony formation assays (C). D The impact of Linc00511 silencing on A549 and PC9 cell apoptosis was assessed by flow cytometric analysis. Transwell assays were used to verify the changes in the migratory (E) and invasive (F) abilities of A549 and PC9 cells after Linc00511 knockdown. *P < 0.05, **P < 0.01, ***P < 0.001 versus si-nc, Scale bars, 50 μm

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BMC Pulmonary Medicine

ISSN: 1471-2466

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