Table 3 Comorbidities of interest for nontuberculous mycobacteria infection in total study population matching for age, sex, income, and region
Comorbidities | NTM (N = 893) n(%) | Non-NTM (N = 3572) n(%) | Odds ratio [95% CI] | p value | ||
|---|---|---|---|---|---|---|
Diseases of the circulatory system | ||||||
Hypertension | 341 (38.2) | 1297 (37.3) | 1.10 [0.92–1.32] | 0.2922 | ||
Chronic heart failure | 88 (9.9) | 371 (10.9) | 0.93 [0.71–1.20] | 0.5685 | ||
Ischemic heart disease | 174 (19.5) | 533 (15.4) | 1.45 [1.18–1.78] | 0.0005 | ||
Arrhythmia | 99 (11.1) | 228 (6.6) | 1.87 [1.45–2.41] | < 0.0001 | ||
Endocrine, nutritional, and metabolic diseases | ||||||
Diabetes mellitus | 312 (34.9) | 936 (26.9) | 1.65 [1.38–1.96] | < 0.0001 | ||
Dyslipidemia | 437 (48.9) | 1388 (39.1) | 1.62 [1.38–1.90] | < 0.0001 | ||
Diseases of the respiratory system | ||||||
Acute sinusitis | 357 (40.0) | 1029 (28.8) | 1.67 [1.43–1.95] | < 0.0001 | ||
Chronic sinusitis | 285 (31.9) | 615 (17.2) | 2.27 [1.92–2.68] | < 0.0001 | ||
COPD | 168 (18.8) | 155 (4.4) | 6.42 [4.97–8.29] | < 0.0001 | ||
Diffuse pan-bronchiolitis | 50 (5.6) | 33 (0.9) | 6.62 [4.21–10.42] | < 0.0001 | ||
Asthma | 446 (49.9) | 986 (27.9) | 2.75 [2.36–3.22] | < 0.0001 | ||
Bronchiectasis | 246 (27.5) | 59 (1.8) | 26.79 [19.69–36.45] | < 0.0001 | ||
Interstitial pneumonia | 32 (3.6) | 9 (0.2) | 15.10 [7.15–31.89] | < 0.0001 | ||
Diseases of the musculoskeletal system | ||||||
Rheumatoid arthritis | 85 (9.5) | 238 (6.7) | 1.49 [1.14–1.95] | 0.0031 | ||
Osteoporosis | 244 (27.3) | 732 (20.9) | 1.80 [1.45–2.23] | < 0.0001 | ||
Bone fracture | 224 (25.1) | 656 (18.8) | 1.52 [1.27–1.81] | < 0.0001 | ||
Diseases of the digestive system | ||||||
Chronic viral hepatitis | 23 (2.6) | 45 (1.3) | 2.07 [1.24–3.46] | 0.0052 | ||
GERD | 559 (62.6) | 1521 (42.7) | 2.35 [2.01–2.74] | < 0.0001 | ||
Diseases of the genitourinary system | ||||||
Chronic kidney disease | 33 (3.7) | 81 (2.4) | 1.65 [1.09–2.51] | 0.0176 | ||
Diseases of the skin and subcutaneous tissue | ||||||
Atopic dermatitis | 97 (10.9) | 220 (6.2) | 1.86 [1.45–2.39] | < 0.0001 | ||
Seborrheic dermatitis | 123 (13.8) | 372 (10.5) | 1.38 [1.10–1.71] | 0.0045 | ||
Contact dermatitis | 564 (63.2) | 1909 (53.6) | 1.50 [1.29–1.75] | < 0.0001 | ||
Other dermatitis | 195 (21.8) | 599 (16.8) | 1.39 [1.16–1.66] | 0.0004 | ||
Urticaria | 311 (34.8) | 1032 (28.9) | 1.32 [1.13–1.54] | 0.0006 | ||
Mental and behavioral disorders | 464 (52.0) | 1543 (43.8) | 1.50 [1.28–1.76] | < 0.0001 | ||
Neoplasms | 187 (20.9) | 345 (10.1) | 2.65 [2.16–3.26] | < 0.0001 | ||