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Table 4 Comorbidities of interest for nontuberculous mycobacteria infection according to sex matching for age, sex, income, and region

From: Comorbidities of nontuberculous mycobacteria infection in Korean adults: results from the National Health Insurance Service–National Sample Cohort (NHIS–NSC) database

Comorbidities

Men

Women

 

NTM (N = 379)*

Non-NTM (n = 1516)*

Odds ratio [95% CI]

p value

NTM (n = 514)*

Non-NTM (n = 2056)*

Odds ratio [95% CI]

p value

Diseases of the circulatory system

 Hypertension

155 (40.9)

600 (39.6)

1.04 [0.80–1.37]

0.7587

186 (36.2)

697 (33.9)

1.16 [0.91–1.48]

0.2457

 Chronic heart failure

42 (11.1)

167 (11.0)

0.98 [0.67–1.43]

0.9236

46 (8.9)

204 (9.9)

0.88 [0.62–1.27]

0.4977

 Ischemic heart disease

74 (19.5)

249 (16.4)

1.24 [0.91–1.70]

0.1678

100 (19.5)

284 (13.8)

1.63 [1.24–2.15]

0.0005

 Arrhythmia

47 (12.4)

96 (6.3)

2.17 [1.48–3.19]

 < 0.0001

52 (10.1)

132 (6.4)

1.67 [1.18–2.35]

0.0035

Endocrine, nutritional, and metabolic diseases

 Diabetes mellitus

143 (37.7)

445 (29.4)

1.54 [1.19–2.01]

0.0011

169 (32.9)

491 (23.9)

1.74 [1.37–2.20]

 < 0.0001

 Dyslipidemia

184 (48.5)

592 (39.1)

1.55 [1.21–1.99]

0.0005

253 (49.2)

796 (38.7)

1.67 [1.35–2.07]

 < 0.0001

Diseases of the respiratory system

 Acute sinusitis

129 (34.0)

332 (21.9)

1.84 [1.44–2.36]

 < 0.0001

228 (44.4)

697 (33.9)

1.57 [1.29–1.92]

 < 0.0001

 Chronic sinusitis

105 (27.7)

211 (13.9)

2.38 [1.82–3.12]

 < 0.0001

180 (35.0)

404 (19.6)

2.21 [1.79–2.73]

 < 0.0001

 COPD

99 (26.1)

100 (6.6)

6.66 [4.70–9.43]

 < 0.0001

69 (13.4)

55 (2.7)

6.35 [4.32–9.34]

 < 0.0001

 Diffuse pan-bronchiolitis

31 (8.2)

16 (1.1)

8.77 [4.69–16.41]

 < 0.0001

19 (3.7)

17 (0.8)

4.74 [2.43–9.24]

 < 0.0001

 Asthma

180 (47.5)

375 (24.7)

2.95 [2.31–3.76]

 < 0.0001

266 (51.8)

611 (29.7)

2.64 [2.15–3.23]

 < 0.0001

 Bronchiectasis

76 (20.1)

19 (1.3)

20.97 [12.41–35.44]

 < 0.0001

170 (33.1)

40 (1.9)

30.55 [20.88–44.71]

 < 0.0001

 Interstitial pneumonia

17 (4.5)

4 (0.3)

18.41 [6.09–55.65]

 < 0.0001

15 (2.9)

5 (0.2)

12.58 [4.53–34.91]

 < 0.0001

Diseases of the musculoskeletal system

 Rheumatoid arthritis

29 (7.7)

61 (4.0)

1.99 [1.25–3.18]

0.004

56 (10.9)

177 (8.6)

1.31 [0.95–1.81]

0.1031

 Osteoporosis

35 (9.2)

104 (6.9)

1.40 [0.91–2.16]

0.1266

209 (40.7)

628 (30.5)

1.97 [1.53–2.52]

 < 0.0001

 Bone fracture

83 (21.9)

246 (16.2)

1.45 [1.09–1.92]

0.0102

141 (27.4)

410 (19.9)

1.59 [1.26–2.02]

0.0001

Diseases of the digestive system

 Chronic viral hepatitis

14 (3.7)

31 (2.0)

1.82 [0.96–3.48]

0.0688

9 (1.8)

14 (0.7)

2.60 [1.12–6.06]

0.0266

 GERD

209 (55.1)

575 (37.9)

2.09 [1.65–2.65]

 < 0.0001

350 (68.1)

946 (46.0)

2.57 [2.09–3.17]

 < 0.0001

Diseases of the genitourinary system

 Chronic kidney disease

16 (4.2)

41 (2.7)

1.57 [0.86–2.86]

0.1402

17 (3.3)

40 (1.9)

1.73 [0.97–3.09]

0.0631

Diseases of the skin and subcutaneous tissue

 Atopic dermatitis

33 (8.7)

74 (4.9)

1.86 [1.21–2.85]

0.0046

64 (12.5)

146 (7.1)

1.86 [1.36–2.54]

 < 0.0001

 Seborrheic dermatitis

64 (16.9)

202 (13.3)

1.32 [0.97–1.80]

0.0816

59 (11.5)

170 (8.3)

1.44 [1.05–1.97]

0.0229

 Contact dermatitis

221 (58.3)

720 (47.5)

1.57 [1.24–1.98]

0.0002

343 (66.7)

1189 (57.8)

1.46 [1.19–1.79]

0.0002

 Other dermatitis

83 (21.9)

236 (15.6)

1.52 [1.15–2.03]

0.0037

112 (21.8)

363 (17.7)

1.30 [1.02–1.65]

0.0313

 Urticaria

119 (31.4)

383 (25.3)

1.36 [1.06–1.74]

0.0169

192 (37.4)

649 (31.6)

1.29 [1.06–1.59]

0.0124

 Mental and behavioral disorders

161 (42.5)

545 (35.9)

1.35 [1.05–1.74]

0.0175

303 (58.9)

998 (48.5)

1.61 [1.30–1.98]

 < 0.0001

 Neoplasms

98 (25.9)

174 (11.5)

3.07 [2.26–4.17]

 < 0.0001

89 (17.3)

171 (8.3)

2.39 [1.80–3.17]

 < 0.0001

  1. *Data are presented as number (%). In the logistic regression model, sex, age, region of residence, and income level were adjusted
  2. COPD, Chronic obstructive pulmonary disease, GERD, Gastroesophageal reflux disease, NTM, Nontuberculous mycobacteria infection