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Table 4 The distribution of microorganisms at the genera level that were found in the samples of PTB patients

From: The performance of detecting Mycobacterium tuberculosis complex in lung biopsy tissue by metagenomic next-generation sequencing

Genera

Reads

α* (%)

β*

γ*

Z-score

MTBC

81,988

53.6623

36/92

36/36

4.9093

Candida

13,731

8.9871

3/92

1/36

0.5308

Aspergillus

11,596

7.5898

3/92

3/36

0.3938

Nakaseomyces

10,961

7.1741

1/92

1/36

0.3531

Human gammaherpesvirus 4

10,727

7.0210

3/92

3/36

0.3381

Mycoplasma

7772

5.0869

2/92

2/36

0.1485

Prevotella

6241

4.0848

5/92

5/36

0.0503

Haemophilus

2340

1.5316

4/92

4/36

−0.1999

Human alphaherpesvirus 1

1784

1.1677

2/92

2/36

−0.2356

Neisseria

1505

0.9850

3/92

3/36

−0.2535

Streptococcus

1502

0.9831

4/92

4/36

−0.2537

Veillonella

1486

0.9726

1/92

1/36

−0.2547

Mycolicibacter

300

0.1964

1/92

1/36

−0.3308

Primate bocaparvovirus 1

258

0.1689

1/92

1/36

−0.3335

Capnocytophag

190

0.1244

2/92

2/36

−0.3378

Actinomyces

168

0.1100

4/92

4/36

−0.3393

Human betaherpesvirus 5

79

0.0517

3/92

3/36

−0.345

Human betaherpesvirus 6B

58

0.0380

1/92

1/36

−0.3463

Pneumocystis

30

0.0196

3/92

3/36

−0.3481

Staphylococcus

23

0.0151

1/92

1/36

−0.3486

Torque teno virus

15

0.0098

2/92

2/36

−0.3491

Cardiobacteriu

11

0.0071

1/92

1/36

−0.3493

Acinetobacter

11

0.0071

2/92

1/36

−0.3493

Torque teno virus 16

4

0.0026

1/92

1/36

−0.3498

Rothia

3

0.0020

1/92

1/36

−0.3498

Klebsiella

1

0.00060

1/92

1/36

−0.3500

Hepatitis B virus

1

0.00060

1/92

1/36

−0.3500

  1. *In the column of α, β and γ refer to the ratio of each pathogen sequenced read in total read, frequency of each pathogen, and patients of each pathogen