Table 2 Included studies
Author/trial ID | Country/region | Description of population | Tests assessed |
|---|---|---|---|
Abubakar et al. [17] | UK | Migrants, Contacts | 1. QFT with 4R 2. QFT with 6H 3. QFT with 3HP 4. TST with 4R 5. TST with 6H 6. TST with 3HP 7. CXR |
Al Abri et al. [20] | Oman | Migrants | TST QFT-GIT T-SPOT.TB CXR |
Auguste et al. [16] | UK | Migrants, Immunocompromised, Children | TST/INH TST/RIF IGRA/INH IGRA/RIF SEQ/INH SEQ/RIF (SEQÂ =Â BCÂ +Â TST at time of medical examination) No intervention |
Campbell et al. [13] | Canada | Migrants | Base case (no screening or treatment for LTBI) IGRA/INH TST/INH |
Campbell et al. [14] | Canada | Migrants | Base case (BC): CXR + medical history + symptom screen BC + TST/INH BC + TST/RIF BC + IGRA/INH BC + IGRA/RIF SEQ/INH (SEQ = BC + TST at time of medical examination) SEQ/RIF |
Campbell et al.a [15] | Canada (British Columbia) | Migrants | QFT, TST |
Capocci et al. [22] | UK | HIV+ | NICE Guideline (not in abstract but taken from guideline) IGRAÂ +Â TST only if CD4Â <Â 500 BHIVA Guideline (not in abstract but taken from guideline) IGRA test only if from sSA: ARTÂ <Â 2 years from MI: CD4Â <Â 400 and ARTÂ <Â 2 years from low TB incidence country:CD4Â <Â 350 and ARTÂ <Â 6Â months |
Capocci et al. [23] | UK | HIV+ | NICE Guideline (not in abstract but taken from guideline) IGRAÂ +Â TST only if CD4Â <Â 500 BHIVA Guideline (not in abstract but taken from guideline) IGRA test only if from sSA: ARTÂ <Â 2 years from MI: CD4Â <Â 400 and ARTÂ <Â 2 years from low TB incidence country:CD4Â <Â 350 and ARTÂ <Â 6Â months |
Capocci et al. [24] | UK | HIV+ | Testing all patients IGRA for all NICE Guideline IGRAÂ +Â TST only if CD4Â <Â 500 BHIVA Guideline IGRA test only if from sSA: ARTÂ <Â 2 years from MI: CD4Â <Â 400 and ARTÂ <Â 2 years from low TB incidence country:CD4Â <Â 350 and ARTÂ <Â 6Â months |
Capocci et al. [25] | UK | HIV+ | TST, IGRA |
Capocci et al. [26] | UK | HIV+ | TST, IGRA, CXR |
Capocci et al. [27] | UK | HIV+ | TST, IGRA, CXR |
Eralp et al. [35] | UK | Healthcare workers | TST IGRA TSTÂ +Â IGRA (X-ray used to confirm +ve test result) |
Goodell et al. [12] | USA | Migrants | QFT, TSPOT, TST, CXR |
Hayama et al. [30] | UK | Contacts | TST alone, IGRA (QFT-GIT or T-SPOT) alone, TST +ve followed by IGRA, TST −ve followed by IGRA |
Jo et al. [11] | USA | Migrants | TST, IGRA |
Kowada [18] | Japan | Migrants | TST QFT T-SPOT TST/QFT TST/T-SPOT CXR |
Kowada [19] | Japan | Migrants, HIV+, contacts | TST QFT T-SPOT TST/QFT TST/T-SPOT CXR |
Kowada [21] | Japan | Healthcare workers | For LTBI: TST, QFT For active TB: CXR |
Kowada [28] | Japan | HIV+ | QFT, TST, TST/QFT, CXR |
Kowada [29] | Japan | Other (care home residents) | TST QFT T-SPOT CXR |
Kowada [31] | Japan | Contacts | IGRA (QFT-GIT or T-SPOT), TST |
Kowada [32] | Japan | Immunocompromised | QFR TSPOT TST CXR |
Kowada [36] | Japan (assumed) | Healthcare workers | Annual QFT alone vs an initial QFT followed by annual CXR |
Kowada [38] | Japan (assumed) | Other (Mental health patients who are smokers) | QFT T-SPOT TST TST followed by QFT TST followed by T-SPOT CXR No screening |
Kowada [40] | Japan | Children | QFT TST CXR |
Laskin et al. [33] | USA | Immunocompromised | TST IGRA Questionnaire |
Li et al. [39] | Hong Kong | Other (Older people on entry to residential care) | QFT followed by confirmatory CXR and then smear test |
USA | Migrants, contacts, immunocompromised | 1. QFT with 4R 2. QFT with 6H 3. QFT with 3HP 4. TST with 4R 5. TST with 6H 6. TST with 3HP 7. CXR | |
Png et al. [37] | Tertiary care hospital in Singapore | Healthcare workers | QFT |
Tasillo et al. [10] | USA | Migrants, HIV+ | IGRA |
Van der Have et al. [34] | Europe | Immuoncompromised | TST with CXR TST with CXR followed by QFT |