Fig. 4

Changes in medication prescription over the post-index period. ICS: inhaled corticosteroids; LABA: long-acting beta-adrenergic receptor antagonists. Antimicrobials refer to respiratory quinolones and 14- and 15-member ring macrolides only. White box: Index month (N = 4,860); Black box Month 3 (N = 1,693); Black box Month 6 (N = 1,491); Black box Month 9 (N = 1,392); Black box Month 12 (N = 1,317). All percentages are expressed using the number of participants taking any medication of interest as the denominator (either alone or in combination with central antitussives). Full data are provided in Additional file 1: Table 3