Skip to main content

Table 6 Treatments prescribed during the index month

From: Clinical characteristics and drug utilisation patterns in patients with chronic cough: a retrospective cohort study using a Japanese claims database

 

Population ‘All’

Population 1

Population 2

Other coughs

Cough-variant asthma

Atopic/allergic cough

 

N = 6,038

N = 3,500

N = 2,538

N = 1,444

N = 1,026

N = 105

Any medication of interest

4,860 (80.5%)

3,115 (89.0%)

1,745 (68.8%)

997 (69.0%)

722 (70.4%)

76 (72.4%)

Central antitussives only

194 (4.0%)

169 (5.4%)

25 (1.4%)

21 (2.1%)

4 (0.6%)

0 (0.0%)

Antiallergic agents (all)

2,588 (53.3%)

1,628 (52.3%)

960 (55.0%)

503 (50.5%)

429 (59.4%)

52 (68.4%)

 Without central antitussives

2,493 (51.3%)

1,544 (49.6%)

949 (54.4%)

496 (49.7%)

427 (59.1%)

51 (67.1%)

 In combination with central antitussives

95 (2.0%)

84 (2.7%)

11 (0.6%)

7 (0.7%)

2 (0.3%)

1 (1.3%)

Expectorant (all)

2,331 (48.0%)

1,654 (53.1%)

677 (38.8%)

402 (40.3%)

281 (38.9%)

24 (31.6%)

 Without central antitussives

1,990 (40.9%)

1,392 (44.7%)

598 (34.3%)

348 (34.9%)

256 (35.5%)

21 (27.6%)

 In combination with central antitussives

341 (7.0%)

262 (8.4%)

79 (4.5%)

54 (5.4%)

25 (3.5%)

3 (3.9%)

Antimicrobialsa (all)

1,672 (34.4%)

1,245 (40.0%)

427 (24.5%)

271 (27.2%)

161 (22.3%)

12 (15.8%)

 Without central antitussives

1,224 (25.2%)

886 (28.4%)

338 (19.4%)

205 (20.6%)

138 (19.1%)

10 (13.2%)

 In combination with central antitussives

448 (9.2%)

359 (11.5%)

89 (5.1%)

66 (6.6%)

23 (3.2%)

2 (2.6%)

ICS and LABA combination (all)

1,404 (28.9%)

901 (28.9%)

503 (28.8%)

198 (19.9%)

309 (42.8%)

25 (32.9%)

 Without central antitussives

1,049 (21.6%)

622 (20.0%)

427 (24.5%)

158 (15.8%)

265 (36.7%)

23 (30.3%)

 In combination with central antitussives

355 (7.3%)

279 (9.0%)

76 (4.4%)

40 (4.0%)

44 (6.1%)

2 (2.6%)

Herbal medicine (all)

1,113 (22.9%)

781 (25.1%)

332 (19.0%)

264 (26.5%)

67 (9.3%)

8 (10.5%)

 Without central antitussives

1,047 (21.5%)

723 (23.2%)

324 (18.6%)

258 (25.9%)

66 (9.1%)

6 (7.9%)

 In combination with central antitussives

66 (1.4%)

58 (1.9%)

8 (0.5%)

6 (0.6%)

1 (0.1%)

2 (2.6%)

Corticosteroids (all)

1,080 (22.2%)

636 (20.4%)

444 (25.4%)

259 (26.0%)

176 (24.4%)

15 (19.7%)

 Without central antitussives

716 (14.7%)

366 (11.7%)

350 (20.1%)

197 (19.8%)

150 (20.8%)

11 (14.5%)

 In combination with central antitussives

364 (7.5%)

270 (8.7%)

94 (5.4%)

62 (6.2%)

26 (3.6%)

4 (5.3%)

Bronchodilatorsb (all)

914 (18.8%)

694 (22.3%)

220 (12.6%)

124 (12.4%)

99 (13.7%)

8 (10.5%)

 Without central antitussives

287 (5.9%)

170 (5.5%)

117 (6.7%%))

62 (6.2%)

60 (8.3%)

2 (2.6%)

 In combination with central antitussives

627 (12.9%)

524 (16.8%)

103 (5.9%)

62 (6.2%)

39 (5.4%)

6 (7.9%)

Drugs for peptic ulcer treatment (all)

718 (14.8%)

436 (14.0%)

282 (16.2%)

145 (14.5%)

127 (17.6%)

18 (23.7%)

 Without central antitussives

691 (14.2%)

412 (13.2%)

279 (16.0%)

143 (14.3%)

126 (17.5%)

18 (23.7%)

 In combination with central antitussives

27 (0.6%)

24 (0.8%)

3 (0.2%)

2 (0.2%)

1 (0.1%)

0 (0.0%)

Drugs for improvement of GI motility function (all)

210 (4.3%)

107 (3.4%)

103 (5.9%)

55 (5.5%)

43 (6.0%)

8 (10.5%)

 Without central antitussives

205 (4.2%)

102 (3.3%)

103 (5.9%)

55 (5.5%)

43 (6.0%)

8 (10.5%)

 In combination with central antitussives

5 (0.1%)

5 (0.2%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

  1. ICS Inhaled corticosteroids, LABA Long-acting beta-adrenergic receptor antagonists, GI Gastrointestinal
  2. All percentages are expressed using the number of participants taking any medication of interest as the denominator
  3. aRespiratory quinolones and 14- and 15-member ring macrolides only
  4. bExcluding participants using long-acting beta-adrenergic receptor antagonists in combination with inhaled corticosteroids