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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: CircRNA has_circ_0017109 promotes lung tumor progression via activation of Wnt/β-catenin signaling due to modulating miR-671-5p/FZD4 axis

Fig. 1

Circ_0017109 is upregulated in NSCLC and associated with poor prognosis in NSCLC patients. A Expression of circ_0017109 in normal lung tissues and NSCLC tumor samples of GSE101586 and GSE112214 (GEO). B Circ_0017109 levels within 50 pairs of NSCLC samples and matched non-carcinoma samples. C Circ_0017109 levels within NSCLC cells, (A549, CALU3, H1229 and CALU6) and human normal bronchial epithelial cells (HBE). D GAPDH and circ_0017109 levels in the RNA samples from H1229 and A549 cell lines with or without RNase R treatment. E RNA levels of circ_0017109, U6 (nuclear control), and GAPDH (cytoplasmic control) in the cytoplasmic and nuclear fraction of H1229 and A549 cells. F The association of NSCLC patient overall survival and circ_0017109 expression level. *, P < 0.05, and ***, P < 0.001

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BMC Pulmonary Medicine

ISSN: 1471-2466

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