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Table 2 Subgroup characteristics according to FEV1 50%

From: Clinical values of diaphragmatic movement in patients with chronic obstructive pulmonary disease

 

< 6.7 cm

n=26

≥ 6.7 cm

n=34

 

FEV1 < 50%

n=14

FEV1 ≥ 50%

n=12

p-value

FEV1 < 50%

n=12

FEV1 ≥ 50%

n=22

p-value

Age (years)

65.0 ± 7.8

72.7 ± 6.2

0.011

69.8 ± 7.2

70.9 ± 6.2

0.627

Sex (male)

14 (100)

12 (100)

 

11 (91.7)

22 (100)

0.169

Smoking

  

0.292

  

0.655

 Never

6 (42.9)

6 (50.0)

 

4 (33.3)

10 (45.5)

 Current

1 (7.1)

3 (25.0)

 

3 (25.0)

3 (13.6)

 Former

7 (50.0)

3 (25.0)

 

5 (41.7)

9 (40.9)

mMRC

  

0.407

  

0.014

 0

0

0

 

0 (0)

0

 1

3 (21.4)

4 (33.3)

 

1 (8.3)

13 (59.1)

 2

7 (50.0)

7 (58.3)

 

9 (75.0)

8 (36.4)

 3

4 (28.6)

1 (8.3)

 

2 (16.7)

1 (4.5)

SGRQ

38.3 ± 13.8

32.2 ± 16.2

0.306

37.5 ± 14.4

27.8 ± 15.1

0.080

GOLD

  

<0.001

  

<0.001

 1 (mild)

0 (0)

1 (8.3)

 

0 (0)

4 (18.2)

 2 (moderate)

1 (7.1)

11 (91.7)

 

1 (8.3)

18 (81.8)

 3 (severe)

9 (64.3)

0 (0)

 

11 (91.7)

0 (0)

 4 (very severe)

4 (28.6)

0 (0)

 

0 (0)

0 (0)

BMI (kg/m2)

22.2 ± 3.4

23.5 ± 2.3

0.302

22.9 ± 2.6

23.3 ± 3.5

0.753

Percent body fat (%)

22.7±8.1

26.2±6.5

0.245

26.2±7.5

25.4±6.1

0.764

PFT

 FEV1

37.0 ± 8.7

63.4 ± 9.9

<0.001

41.8 ± 5.6

69.2 ± 13.0

<0.001

 FVC

73.5 ± 21.4

79.3 ± 16.3

0.454

86.2 ± 14.2

85.9 ± 16.5

0.958

 FEV1/FVC

40.1 ± 14.7

55.4 ± 11.4

0.007

34.7 ± 5.5

56.8 ± 10.813

<0.001

 Maximum inspiratory pressure (cmH2O)

70.2 ± 29.4

64.4 ± 20.5

0.572

72.5 ± 32.1

94.1 ± 24.1

0.034

 Maximum expiratory pressure (cmH2O)

80.9 ± 28.4

85.7 ± 36.7

0.718

76.0 ± 27.2

86.8 ± 22.1

0.218

 Peak expiratory flow rate (L/min)

183.3 ± 80.4

275.8 ± 113.8

0.027

166.7 ± 61.5

307.1 ± 129.5

0.002

6MWT

 Total distance of 6MWT (m)

404.3 ± 164.0

432.7 ± 160.8

0.668

456.7 ± 69.7

513.9 ± 60.3

0.018

 SpO2 before 6MWT (%)

93.3 ± 2.9

95.3 ± 1.7

0.066

94.4 ± 1.7

95.8 ± 1.4

0.014

 SpO2 after 6MWT (%)

85.9 ± 6.5

91.5 ± 2.2

0.011

85.7 ± 5.1

90.5 ± 5.0

0.013

 Interruption of the 6MWT (n)

2 (14.3)

2 (16.7)

0.867

0 (0)

0 (0)

 

Diaphragm (cm)

 Right forced excursion*

5.0 ± 1.4

5.6 ± 0.8

0.188

7.8 ± 0.8

8.6 ± 1.5

0.108

 Left forced excursion*

6.2 ± 1.6

7.4 ± 1.0

0.038

7.7 ± 1.3

7.6 ± 1.3

0.812

 Right thickness, end-expiration

0.2182 ± 0.0

0.2 ± 0.0

0.192

0.2 ± 0.0

0.2 ± 0.0

0.020

 Left thickness, end-inspiration

0.1 ± 0.1

0.3 ± 0.1

0.920

0.3 ± 0.1

0.4 ± 0.1

0.284

 Rigth thicknsee Fraction (%)

72.1 ± 38.6

58.9 ± 15.3

0.254

89.4 ± 31.8

82.8 ± 28.9

0.542

 Left thickness Fraction (%)

71.4 ± 32.2

61.5 ± 19.3

0.358

67.3 ± 27.8

118.7 ± 258.5

0.500

  1. Abbreviations: 6MWT 6-minute walk test, BMI Body mass index, FEV1 Forced expiratory volume in the first second, FVC Forced vital capacity, GOLD Global Initiative for Chronic Obstructive Lung Disease, mMRC Modified Medical Research Council, SGRQ St. George's Respiratory Questionnaire, PFT Pulmonary function test; *supine position
  2. After dividing the total patients based on ROC < 6.7, each group was divided into FEV1 50% standard and compared the characteristics of each subgroup.