Table 1 Basic characteristic and clinical description of lung transplant recipients

Age, years

63.50

(49.50 to 67.75)

57.0

(49.0 to 66.0)

63.0

(57.25 to 69.50)

61.0

(55.0 to 66.0)

0.322

Gender

0.254

 Male, n(%)

30 (81.08%)

30 (69.77%)

18 (90%)

57 (81.43%)

 Female, n(%)

7 (18.92%)

13 (30.23%)

2 (10%)

13 (18.57%)

Body mass index (kg/m2)

19.01 ± 4.01

20.93 ± 3.57

21.25 ± 3.46

20.53 ± 3.62

0.069

Time from LTR to

sample collection (Days)

39.0

(24.0 to 196.0)

404.0

(112.0 to 830.0)

920.50

(626.75 to 1856.50)

382.50

(74.75 to 799.25)

 < 0.001

Type of transplantation

0.094

 Single lung, n(%)

16 (43.24%)

22 (51.16%)

11 (55%)

47 (67.14%)

 Bilateral lung, n(%)

21 (56.76%)

21 (48.84%)

9 (45%)

23 (32.86%)

PRA status

0.022

 Positive ( +)

6 (16.22%)

2 (4.65%)

3 (15%)

2 (2.86%)

 Negative (-)

31 (83.78%)

41 (95.35%)

17 (85%)

68 (9.71%)

FEV1%pred change rate (%)

-25.39

(-39.56 to -17.99)

-10.12

(-19.26 to -5.12)

-21.88

(-32.05 to -11.68)

-3.56

(-8.10 to -0.65)

 < 0.001

FEV1/FVC% change rate (%)

-11.37

(-19.14 to -0.48)

-5.37

(-12.79 to 0)

-10.53

(-23.28 to 0.09)

-1.41

(-6.46 to 1.83)

 < 0.001

FVC%pred change rate (%)

-22.0

(-40.7 to -13.07)

-7.69

(-18.13 to -0.16)

-19.71

(-29.69 to -10.17)

-3.25

(-9.80 to 0)

 < 0.001

DLCO%pred change rate (%)

-16.57

(-37.93 to -10.22)

-7.76

(-15.20 to -1.05)

-19.73

(-23.83 to -6.36)

-2.0

(-8.35 to -1.90)

 < 0.001

Prior episode of acute rejection,

n (%)

10 (27.01%)

3 (6.98%)

12 (60%)

1 (1.43%)

 < 0.001

Gastroesophageal reflux disease, n (%)

0

0

3 (15%)

1 (1.43%)

0.001

Cytomegalovirus IgG status, n (%)

0.460

 D + /R + 

31(83.78%)

32(74.42%)

17(85%)

50(71.43%)

 D − /R − 

2(5.41%)

5(11.63%)

1(5%)

7(10%)

 D + /R − 

3(8.11%)

2(4.65%)

2(10%)

3(4.29%)

 D − /R + 

1(2.7%)

4(9.3%)

0

10(14.29%)

Indication for lung transplantation, n (%)

0.080

 Bronchiectasis

4(10.81%)

1(2.33%)

1(5%)

4(5.71%)

 Chronic obstructive pulmonary disease

11(29.73%)

11(25.58%)

11(55%)

21(30%)

 Connective tissue disease related interstitial lung disease

2(5.41%)

6(13.95%)

0

3(4.29%)

 Idiopathic interstitial pulmonary disease

13(35.14%)

14(32.56%)

5(25%)

32(45.71%)

 Pulmonary lymphangioleiomyomatosis

2(5.41%)

3(6.98%)

0

0

 Pulmonary arterial hypertension

0

1(2.33%)

1(5%)

0

 Work-related lung diseases

1(2.7%)

1(2.33%)

0

6(8.57%)

 Others

4(10.81%)

6(13.95%)

2(10%)

4(5.71%)