Table 3 Comparison of clinical characteristics and polysomnographic data in people with cystic fibrosis with and without obstructive sleep apnea
From: Obstructive sleep apnea and nocturnal hypoxemia in adult patients with cystic fibrosis
|  | OSA (n = 21) | No OSA (n = 31) | p value |
|---|---|---|---|
Age, years | 32.6 ± 9.6 | 29.4 ± 6.5 | 0.318 |
AHI, events/h | 8.6 ± 3.4 | 1.9 ± 1.3 | 0.000 |
AHI REM, events/h | 18.3 ± 11.2 | 5.2 ± 4.7 | 0.000 |
AHI NREM, events/h | 6.0 ± 3.8 | 1.2 ± 1.0 | 0.000 |
ODI, events/h | 8.4 ± 3.6 | 1.9 ± 1.1 | 0.000 |
ODI REM, events/h | 25.5 ± 30.1 | 5.5 ± 4.8 | 0.000 |
ODI NREM, events/h | 5.8 ± 4.0 | 1.2 ± 0.9 | 0.000 |
Arousal index, events/h | 22.4 ± 9.8 | 16.4 ± 10.1 | 0.039 |
ESS score | 6.8 ± 4.3 | 6.7 ± 3.6 | 0.888 |
TST, min | 302.5 ± 35.5 | 298.5 ± 48.4 | 0.621 |
Sleep efficiency, % | 76.3 ± 9.3 | 74.5 ± 10.9 | 0.539 |
Sleep latency, min | 61.5 ± 32.9 | 72.7 ± 39.5 | 0.520 |
WASO, min | 34.2 ± 17.9 | 33.6 ± 33.4 | 0.176 |
Sleep stages, % TST | Â | Â | Â |
N1 | 3.0 ± 1.9 | 3.1 ± 1.7 | 0.608 |
N2 | 49.4 ± 6.2 | 51.9 ± 8.7 | 0.261 |
N3 | 25.2 ± 7.4 | 25.1 ± 9.8 | 0.668 |
REM | 19.8 ± 5.4 | 17.1 ± 6.9 | 0.134 |
Nocturnal mean SpO2, % | 91.0 ± 2.8 | 92.8 ± 1.5 | 0.025 |
Nocturnal minimum SpO2, % | 83.8 ± 3.6 | 89.1 ± 2.1 | 0.000 |
spO2 < 90%, % TST | 30.6 ± 36.7 | 1.7 ± 4.4 | 0.000 |
spO2 < 90%, min | 94.9 ± 115.6 | 5.0 ± 11.8 | 0.000 |
Nocturnal respiratory rate, breaths/min | 21.0 ± 4.3 | 21.6 ± 3.8 | 0.613 |
Nocturnal heart rate, beats/min | 71.8 ± 12.9 | 64.4 ± 10.2 | 0.049 |
BMI, kg/m2 | 21.9 ± 3.7 | 21.2 ± 3.0 | 0.737 |
FEV1, L | 2.0 ± 0.8 | 2.1 ± 0.8 | 0.608 |
FEV1, % predicted | 49.1 ± 14.8 | 54.2 ± 14.7 | 0.233 |
FVC, L | 3.3 ± 1.1 | 3.4 ± 1.0 | 0.920 |
FVC, % predicted | 66.4 ± 17.9 | 71.7 ± 14.9 | 0.252 |
RV, L | 3.2 ± 0.9 | 2.9 ± 0.8 | 0.303 |
RV, % predicted | 179.9 ± 37.7 | 180.0 ± 45.1 | 0.996 |
Awake SpO2, % | 95.4 ± 1.8 | 96.0 ± 1.5 | 0.136 |
Awake pO2, mmHg | 75.7 ± 8.9 | 80.9 ± 8.4 | 0.048 |
Awake pCO2, mmHg | 39.5 ± 2.7 | 38.5 ± 2.8 | 0.256 |
Awake pH | 7.42 ± 0.02 | 7.40 ± 0.03 | 0.023 |
Awake HCO3−, mmol/L | 25.6 ± 1.6 | 24.1 ± 1.7 | 0.003 |