Table 4 Comparison of clinical characteristics and polysomnographic data in people with cystic fibrosis with and without nocturnal hypoxemia
From: Obstructive sleep apnea and nocturnal hypoxemia in adult patients with cystic fibrosis
|  | Hypoxemia (n = 13) | No hypoxemia (n = 39) | p value |
|---|---|---|---|
Age, years | 34.4 ± 10.2 | 29.4 ± 6.8 | 0.120 |
AHI, events/h | 8.8 ± 3.8 | 3.2 ± 3.1 | 0.000 |
AHI REM, events/h | 20.3 ± 11.8 | 7.2 ± 7.3 | 0.001 |
AHI NREM, events/h | 5.8 ± 4.3 | 2.3 ± 2.6 | 0.000 |
ODI, events/h | 9.0 ± 4.0 | 3.1 ± 2.9 | 0.000 |
ODI REM, events/h | 21.5 ± 10.6 | 7.4 ± 7.3 | 0.000 |
ODI NREM, events/h | 6.1 ± 4.8 | 2.1 ± 2.4 | 0.000 |
Arousal index, events/h | 20.9 ± 9.8 | 18.1 ± 10.5 | 0.409 |
ESS score | 5.9 ± 3.0 | 6.8 ± 4.1 | 0.400 |
TST, min | 308.3 ± 21.5 | 297.3 ± 48.4 | 0.575 |
Sleep efficiency, % | 78.0 ± 7.6 | 74.4 ± 10.9 | 0.279 |
Sleep latency, min | 59.9 ± 27.2 | 70.9 ± 39.7 | 0.634 |
WASO, min | 36.8 ± 17.0 | 32.8 ± 30.9 | 0.139 |
Sleep stages, % TST | Â | Â | Â |
N1 | 3.1 ± 1.9 | 3.1 ± 1.7 | 0.916 |
N2 | 48.2 ± 5.3 | 51.7 ± 8.4 | 0.159 |
N3 | 26.9 ± 6.3 | 24.6 ± 9.5 | 0.148 |
REM | 19.1 ± 5.7 | 17.9 ± 6.7 | 0.565 |
Nocturnal mean SpO2, % | 89.6 ± 2.6 | 92.9 ± 1.5 | 0.000 |
Nocturnal minimum SpO2, % | 81.4 ± 2.2 | 88.8 ± 2.0 | 0.000 |
Nocturnal respiratory rate, breaths/min | 22.7 ± 4.6 | 20.1 ± 3.7 | 0.172 |
Nocturnal heart rate, beats/min | 72.9 ± 13.0 | 65.5 ± 11.0 | 0.064 |
BMI, kg/m2 | 21.8 ± 3.9 | 21.4 ± 3.1 | 0.983 |
FEV1, L | 1.7 ± 0.6 | 2.2 ± 0.8 | 0.014 |
FEV1, % predicted | 43.5 ± 13.0 | 55.0 ± 14.4 | 0.014 |
FVC, L | 2.9 ± 0.1 | 3.5 ± 1.0 | 0.046 |
FVC, % predicted | 60.8 ± 16.1 | 72.5 ± 15.2 | 0.023 |
RV, L | 3.4 ± 1.0 | 2.9 ± 0.8 | 0.068 |
RV, % predicted | 196.9 ± 43.2 | 174.3 ± 40.5 | 0.092 |
Awake SpO2, % | 95.0 ± 1.8 | 96.1 ± 1.6 | 0.021 |
Awake pO2, mmHg | 72.5 ± 8.4 | 80.8 ± 8.2 | 0.003 |
Awake pCO2, mmHg | 40.2 ± 2.5 | 38.4 ± 2.7 | 0.051 |
Awake pH | 7.42 ± 0.02 | 7.41 ± 0.03 | 0.175 |
Awake HCO3−, mmol/L | 25.7 ± 1.7 | 24.4 ± 1.7 | 0.017 |