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Table 5 Comparison of clinical characteristics and polysomnographic data in people with cystic fibrosis with or without daytime sleepiness (Epworth Sleepiness Scale score > 10 versus ≤ 10)

From: Obstructive sleep apnea and nocturnal hypoxemia in adult patients with cystic fibrosis

 

ESS score ≥ 10 (n = 8)

ESS score < 10 (n = 44)

p value

Age, years

28.9 ± 4.8

31.0 ± 8.4

0.718

AHI, events/h

4.1 ± 3.2

4.7 ± 4.2

0.833

AHI REM, events/h

7.7 ± 5.4

11.0 ± 10.9

0.970

AHI NREM, events/h

3.2 ± 3.5

3.2 ± 3.5

0.872

ODI, events/h

3.7 ± 2.7

4.7 ± 4.2

0.891

ODI REM, events/h

7.6 ± 5.4

14.4 ± 23.7

0.694

ODI NREM, events/h

2.7 ± 2.8

3.1 ± 3.6

0.911

Arousal index, events/h

22.4 ± 8.2

18.1 ± 10.6

0.292

TST, min

313.4 ± 29.0

297.7 ± 45.3

0.276

Sleep efficiency, %

79.2 ± 8.4

74.6 ± 10.4

0.245

Sleep latency, min

51.3 ± 20.7

71.2 ± 38.7

0.155

WASO, min

30.8 ± 21.5

34.4 ± 29.2

0.813

Sleep stages, % TST

   

N1

2.8 ± 0.9

3.1 ± 1.9

0.970

N2

54.4 ± 5.4

50.2 ± 8.1

0.167

N3

21.9 ± 4.6

25.8 ± 9.3

0.375

REM

18.6 ± 5.6

18.1 ± 6.6

0.833

Nocturnal mean SpO2, %

92.4 ± 1.9

92.0 ± 2.4

0.718

Nocturnal minimum SpO2, %

88.4 ± 3.0

86.7 ± 3.9

0.187

SpO2 < 90%, % TST

7.9 ± 21.0

14.4 ± 28.3

0.133

SpO2 < 90, min

23.0 ± 60.2

44.6 ± 89.5

0.097

Nocturnal respiratory rate, breaths/min

20.5 ± 3.2

21.6 ± 4.1

0.478

Nocturnal heart rate, beats/min

60.9 ± 7.0

68.5 ± 12.2

0.108

BMI, kg/m2

23.4 ± 2.6

21.1 ± 3.1

0.040

FEV1, L

2.1 ± 0.8

2.1 ± 0.8

0.990

FEV1, % predicted

52.0 ± 15.3

52.2 ± 14.9

0.978

FVC, L

3.4 ± 1.2

3.4 ± 1.0

0.897

FVC, % predicted

70.9 ± 18.8

69.3 ± 15.9

0.803

RV, L

2.7 ± 0.6

3.1 ± 0.9

0.329

RV, % predicted

172.8 ± 40.5

181.3 ± 42.5

0.603

Awake SpO2, %

96.4 ± 1.1

95.7 ± 1.7

0.276

Awake pO2, mmHg

78.0 ± 6.1

78.9 ± 9.4

0.789

Awake pCO2, mmHg

38.4 ± 2.9

29.0 ± 2.8

0.591

Awake pH

7.4 ± 0.02

7.4 ± 0.03

0.335

Awake HCO3−, mmol/L

25.1 ± 1.3

24.6 ± 1.9

0.543

  1. Values are mean ± standard deviation
  2. AHI, apnea-hypopnea index; ESS, Epworth Sleepiness Scale; BMI, body mass index; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; HCO3−, bicarbonate; NREM, non-rapid eye movement sleep; ODI, oxygen desaturation index; pCO2, partial pressure of carbon dioxide pressure; pO2, partial pressure of oxygen; RDI, respiratory disturbance index; REM, rapid eye movement sleep; RV, residual volume; SpO2, oxygen saturation; TST, total sleep time; WASO, wake after sleep onset
  3. Bold values denote statistical significance at the p < 0.05 level
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BMC Pulmonary Medicine

ISSN: 1471-2466

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