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Table 2 Diagnostic accuracy of PF ADA and LDH/ADA ratio

From: Diagnostic accuracy of pleural fluid lactate dehydrogenase to adenosine deaminase ratio for tuberculous pleural effusion: an analysis of two cohorts

Testing

AUC (95% CI)

Threshold

Sensitivity (95% CI)

Specificity (95% CI)

The BUFF study

LDH/ADA

0.74 (0.67–0.81)

20

0.74 (0.63–0.84)

0.66 (0.60–0.73)

ADA

0.76 (0.69–0.82)

35 U/L

0.47 (0.34–0.60)

0.86 (0.80–0.90)

The SIMPLE study

LDH/ADA

0.85 (0.76–0.93)

20

0.85 (0.70–0.97)

0.67 (0.60–0.74)

ADA

0.80 (0.71–0.90)

35 U/L

0.61 (0.45–0.76)

0.92 (0.88–0.96)

  1. Abbreviations have been explained in the footnote of Table 1