MRI-assessed diaphragmatic function can predict frequent acute exacerbation of COPD: a prospective observational study based on telehealth-based monitoring system

Table 5 Logistic regression analysis of risk factors associated with the frequency of AECOPD

	Univariate analysis			Multivariate analysis
	OR	95% CI	P	OR	95% CI	P
Age	1.14	1.03–1.25	0.009
BMI	0.70	0.56–0.89	0.003
CAT scores	1.19	1.06–1.34	0.003
6MWD(m)	0.99	0.98–1.00	0.001
FEV1%pred	0.94	0.91–0.97	0.000
FVC%pred	0.95	0.92–0.99	0.004
FEV1/FVC%	0.93	0.89–0.98	0.007
Diaphragmatic dome factor (Insp)	0.01	0.00–4.56	0.125
Diaphragmatic dome factor (Exp)	0.22	0.00–16.10	0.485
Chest wall motion(cm)	0.37	0.15–0.92	0.032	0.37	0.15–0.92	0.032
Change of lung area (cm²)	0.979	0.96–0.99	0.007
Diaphragmatic displacement (cm)	0.45	0.29–0.69	0.000
Diaphragm thickening fraction	0.88	0.83–0.94	0.000	0.89	0.89–0.94	0.000

ECOPD, acute exacerbations of chronic obstructive pulmonary disease; BMI, body mass index; CAT, chronic obstructive pulmonary disease assessment test; 6MWT, 6-min walk test; FEV1, forced expiratory volume at 1 s; FVC, forced vital capacity; OR odds ratio; 95% CI 95% confidence interval; Insp, inspiration; Exp, expiration

ISSN: 1471-2466